Title:
CYCLOPENTANE COMPOUND
Document Type and Number:
WIPO Patent Application WO/2024/075825
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a novel compound that has an OX2R agonist activity. The present invention pertains to a cyclopentane compound represented by formula (I) or a pharmacologically acceptable salt thereof. This compound, or a pharmacologically acceptable salt thereof, has an agonist activity against OX2R, and is useful as a treatment agent, etc., for sleep disorders involving OX2R (e.g., narcolepsy, idiopathic hypersomnia, Kleine-Levin syndrome, hypersomnia associated with a physical disease, hypersomnia associated with a mental disease, hypersomnia associated with a drug or a substance, circadian rhythm sleep-wake disorder, insufficient sleep syndrome, and extended sleep).
Inventors:
KONDO ATSUSHI (JP)
YOSHIDA MASAKO (JP)
MATSUMOTO TSUTOMU (JP)
SHIOGAI AKIHIRO (JP)
OKI TOMOYA (JP)
YOSHIDA MASAKO (JP)
MATSUMOTO TSUTOMU (JP)
SHIOGAI AKIHIRO (JP)
OKI TOMOYA (JP)
Application Number:
PCT/JP2023/036458
Publication Date:
April 11, 2024
Filing Date:
October 06, 2023
Export Citation:
Assignee:
KISSEI PHARMACEUTICAL (JP)
International Classes:
C07C311/07; A61K31/165; A61K31/18; A61K31/277; A61K31/341; A61K31/40; A61K31/4192; A61K31/42; A61K31/421; A61K31/426; A61K31/44; A61K31/505; A61P25/26; A61P43/00; C07D207/06; C07D213/61; C07D239/26; C07D239/30; C07D239/42; C07D249/04; C07D261/02; C07D263/32; C07D277/30; C07D307/54
Domestic Patent References:
| WO2022051583A1 | 2022-03-10 | |||
| WO2021107023A1 | 2021-06-03 | |||
| WO2019117148A1 | 2019-06-20 | |||
| WO2022014680A1 | 2022-01-20 |
Foreign References:
| JP2022064180A | 2022-04-25 | |||
| US20060116421A1 | 2006-06-01 |
Attorney, Agent or Firm:
YANAGI, Nobuko et al. (JP)
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