Title:
CYCLOPROPYL GROUP SUBSTITUTED OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF
Document Type and Number:
WIPO Patent Application WO2005005398
Kind Code:
A3
Abstract:
This invention relates to new oxazolidinones having a cyclopropyl moiety, which are effective against aerobic and anerobic pathogens such as multi-resistant staphylococci, streptococci and enterococci, Bacteroides spp., Clostridia spp. species, as well as acid-fast organisms such as Mycobacterium tuberculosis and other mycobactenial species. The compounds are represented by structural formula: (I): its enantiomer, diastereomer, or pharmaceutically acceptable salt or ester thereof.
Inventors:
FUKUDA YASUMICHI (JP)
Application Number:
PCT/US2004/020734
Publication Date:
April 28, 2005
Filing Date:
June 29, 2004
Export Citation:
Assignee:
MERCK & CO INC (US)
KYORIN SEIYAKU KK (JP)
FUKUDA YASUMICHI (JP)
KYORIN SEIYAKU KK (JP)
FUKUDA YASUMICHI (JP)
International Classes:
A61K31/422; A61P31/04; C07D263/00; C07D413/02; C07D413/10; C07D413/14; C07D417/14; C07D487/08; (IPC1-7): C07D413/14; C07D413/10; C07D487/08; C07D417/14; A61K31/422; A61P31/04
Domestic Patent References:
| WO2004048350A2 | 2004-06-10 | |||
| WO2001094342A1 | 2001-12-13 | |||
| WO1994013649A1 | 1994-06-23 | |||
| WO2003027083A1 | 2003-04-03 |
Foreign References:
| US20040147760A1 | 2004-07-29 | |||
| US5523403A | 1996-06-04 | |||
| EP0352781A2 | 1990-01-31 | |||
| US5736545A | 1998-04-07 |
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