CYSTEINE ANALOGUES SALTS OF AMBROXOL, PREPARATION METHODS AND USES THEREOF

Title:

CYSTEINE ANALOGUES SALTS OF AMBROXOL, PREPARATION METHODS AND USES THEREOF

Document Type and Number:

WIPO Patent Application WO/2005/113492

Kind Code:

A1

Abstract:

The invention relates to cysteine analogues salts of Ambroxol represented by formula (I), wherein: n is 1 or 2, A is as defined in the specification. Their preparation methods, pharmaceutical compositions containing them and their uses in preparation of expectorant are also described. Said preparation methods comprise reacting Ambroxol and cysteine analogues in solvent and then crystallizing.

Inventors:

CEN JUNDA (CN)
ZHONG HUIJUAN (CN)

Application Number:

PCT/CN2005/000685

Publication Date:

December 01, 2005

Filing Date:

May 18, 2005

Export Citation:

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Assignee:

JIANGSU HANSEN PHARMACEUTICAL (CN)
CEN JUNDA (CN)
ZHONG HUIJUAN (CN)

International Classes:

C07C215/44; C07C321/04; C07C323/58; C07C323/59; C07D333/38; (IPC1-7): C07C321/04; C07D333/38

Foreign References:

US4845114A

1989-07-04

Attorney, Agent or Firm:

JEEKAI & PARTNERS (Jinyu Tower A129 West Xuan Wu Men Street, Beijing 1, CN)

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