Title:
CYTOTOXICITY-INDUCING THERAPEUTIC AGENT FOR USE IN TREATMENT OF CANCER
Document Type and Number:
WIPO Patent Application WO/2023/053282
Kind Code:
A1
Abstract:
The present disclosure provides: an anti-cancer agent that contains multispecific antigen-binding molecules, said anti-cancer agent being capable of effectively and selectively mobilizing T cells to target cancer cells, i.e. to cells that express CLDN6 such as cancer cells, and treating cancer through the cytotoxic activity of T cells on target cancer tissue containing cells that express CLDN6; a combination therapy that involves said anti-cancer agent and at least one other anti-cancer agent; and a medicinal composition for use in said combination therapy.
Inventors:
ISHII SHINYA (JP)
KAMIKAWA TAKAYUKI (JP)
KIMURA NAOKI (JP)
KODAMA TATSUSHI (JP)
KAMIKAWA TAKAYUKI (JP)
KIMURA NAOKI (JP)
KODAMA TATSUSHI (JP)
Application Number:
PCT/JP2021/035917
Publication Date:
April 06, 2023
Filing Date:
September 29, 2021
Export Citation:
Assignee:
CHUGAI PHARMACEUTICAL CO LTD (JP)
International Classes:
A61K39/395; A61P35/00; A61P43/00
Domestic Patent References:
| WO2019111871A1 | 2019-06-13 | |||
| WO2019135404A1 | 2019-07-11 | |||
| WO2020067399A1 | 2020-04-02 | |||
| WO2020067419A1 | 2020-04-02 |
Foreign References:
| JP2016500059A | 2016-01-07 | |||
| JP2021168648A | 2021-10-28 |
Attorney, Agent or Firm:
HARUNA, Masao et al. (JP)
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