Title:
D-DOMAIN CONTAINING POLYPEPTIDES AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/099433
Kind Code:
A3
Abstract:
D domain (DD) containing polypeptides (DDpp) that specifically bind targets of interest (e.g., BCMA, CD123, CS1, HER2, AFP, and AFP p26) are provided, as are nucleic acids encoding the DDpp, vectors containing the nucleic acids and host cells containing the nucleic acids and vectors. DDpp such as DDpp fusion proteins, are also provided as are methods of making and using the DDpp. Such uses include, but are not limited to diagnostic and therapeutic applications.
Inventors:
HILBERT DAVID (US)
SWERS JEFFREY (US)
SWERS JEFFREY (US)
Application Number:
PCT/US2018/060887
Publication Date:
March 26, 2020
Filing Date:
November 14, 2018
Export Citation:
Assignee:
ARCELLX INC (US)
International Classes:
C12N15/10; A61K35/17; A61K38/17; C07K16/00; C12Q1/00; C40B40/02
Domestic Patent References:
| WO2016164308A1 | 2016-10-13 |
Foreign References:
| US20160311878A1 | 2016-10-27 |
Attorney, Agent or Firm:
GASZNER, Miklos (US)
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