Title:
D-LUCIFERIN, D-LUCIFERIN DERIVATIVE, PRECURSOR OF THESE COMPOUNDS AND METHOD FOR PRODUCING THESE COMPOUNDS
Document Type and Number:
WIPO Patent Application WO/2022/196819
Kind Code:
A1
Abstract:
The present invention establishes a non-conventional, novel method for producing D-luciferin and a D-luciferin derivative by a multi-stage production process without using expensive 2-cyano-6-hydroxybenzothiazole. The above is achieved by means of a method for producing D-luciferin and a D-luciferin derivative, wherein D-luciferin or a D-luciferin derivative is produced via a precursor that is a novel substituted diaminodithioether represented by formula (1) (wherein X represents H, OCH3 or OH; and each of Y, Z, and W represents H or a monovalent organic group).
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Inventors:
MATSUMOTO KOUICHI (JP)
KOBAYASHI MASAFUMI (JP)
KOBAYASHI MASAFUMI (JP)
Application Number:
PCT/JP2022/012857
Publication Date:
September 22, 2022
Filing Date:
March 18, 2022
Export Citation:
Assignee:
KANTO DENKA KOGYO KK (JP)
UNIV KINKI (JP)
UNIV KINKI (JP)
International Classes:
C07C323/58; C07C319/14
Foreign References:
JP2010180191A | 2010-08-19 | |||
JP2019068817A | 2019-05-09 | |||
JP2007091695A | 2007-04-12 | |||
JP2012533654A | 2012-12-27 | |||
JPS5616480A | 1981-02-17 | |||
CN1911917A | 2007-02-14 | |||
JP2010180191A | 2010-08-19 | |||
JP2019068817A | 2019-05-09 | |||
JP2007091695A | 2007-04-12 | |||
JP2012533654W |
Other References:
J. AM. CHEM. SOC., vol. 83, no. 10, 1961, pages 2402
SCIENTIFIC REPORTS, vol. 6, 2016, pages 24794
J. AM. CHEM. SOC., vol. 142, 2020, pages 16205
ACS APPL. MATER. INTERFACES, vol. 4, 2012, pages 3788
J. LABELLED COMP RADIOPHARM, vol. 28, 1990, pages 209
J. AM. CHEM. SOC., vol. 134, 2012, pages 7604
SCIENTIFIC REPORTS, vol. 6, 2016, pages 24794
J. AM. CHEM. SOC., vol. 142, 2020, pages 16205
ACS APPL. MATER. INTERFACES, vol. 4, 2012, pages 3788
J. LABELLED COMP RADIOPHARM, vol. 28, 1990, pages 209
J. AM. CHEM. SOC., vol. 134, 2012, pages 7604
Attorney, Agent or Firm:
YAMAMOTO, Osamu et al. (JP)
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