Title:
DATA COLLECTION METHOD AND KIT FOR DETERMINING LIKELIHOOD OF DEVELOPING ALZHEIMER'S DISEASE
Document Type and Number:
WIPO Patent Application WO/2024/075828
Kind Code:
A1
Abstract:
A data collection method for determining the likelihood of a subject developing Alzheimer's disease, the method comprising measuring, in a biological specimen of the subject, the proportion of methylated DNA in a CpG island including a cytosine residue selected from the group consisting of cytosine residues at positions 24, 56, 75, 81, 98, 103, 115, 126, 134, 142, 153, and 179 in the base sequence of the promoter region of COASY gene indicated by SEQ ID NO: 1, wherein the proportion being high as compared to a control indicates that the subject has a high likelihood of developing Alzheimer's disease.
Inventors:
KOBAYASHI NOBUYUKI (JP)
Application Number:
PCT/JP2023/036475
Publication Date:
April 11, 2024
Filing Date:
October 06, 2023
Export Citation:
Assignee:
THE JIKEI UNIV (JP)
International Classes:
C12Q1/68; C12N15/12; C12Q1/6883
Attorney, Agent or Firm:
IIDA Masato (JP)
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