Title:
DELIVERY SYSTEM FOR THERAPY COMPRISING HOLLOW SEEDS, PREFERABLY METAL, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO2001013986
Kind Code:
A9
Abstract:
Hollow metal seeds are provided having a therapeutic agent encapsulated therein, e.g., a nucleic acid or cytokine, that diffuses out of the seeds via one or more holes disposed therein and is thereby delivered to target sites, e.g., tumor cells. These hollow metal seeds can be precisely delivered to target sites, e.g., within a tumor, preferably by use of stereotactic guidance, ultrasound, CT, or MRI.
Inventors:
DRITSCHILO ANATOLY (US)
JUNG MIRA (US)
SUBRAMANIAN MANNY R (US)
JUNG MIRA (US)
SUBRAMANIAN MANNY R (US)
Application Number:
PCT/US2000/022780
Publication Date:
September 12, 2002
Filing Date:
August 21, 2000
Export Citation:
Assignee:
UNIV GEORGETOWN (US)
DRITSCHILO ANATOLY (US)
JUNG MIRA (US)
SUBRAMANIAN MANNY R (US)
DRITSCHILO ANATOLY (US)
JUNG MIRA (US)
SUBRAMANIAN MANNY R (US)
International Classes:
A61M36/04; A61K9/00; A61M31/00; A61M36/00; A61M37/00; (IPC1-7): A61M37/00
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