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Title:
DEOXYKETOHEXOSE ISOMERASE AND METHOD FOR PRODUCING DEOXYKETOHEXOSE AND DERIVATIVE THEREOF USING THE SAME
Document Type and Number:
WIPO Patent Application WO/2008/062780
Kind Code:
A1
Abstract:
It is intended to provide 1- or 6-deoxy forms corresponding to all the aldohexoses, ketohexoses and sugar alcohols based on deoxyizumoring, and a method for systematically producing the same. A method for producing a deoxyketohexose and a derivative thereof, characterized by producing a corresponding 1-deoxy-D-ketohexose, 6-deoxy-D-ketohexose, 1-deoxy-L-ketohexose or 6-deoxy-L-ketohexose, which is an objective substance, by epimerization of the 3-position of a 1-deoxy-D-ketohexose, 6-deoxy-D-ketohexose, 1-deoxy-L-ketohexose or 6-deoxy-L-ketohexose, which is a raw material, using a deoxyketohexose isomerase derived from Pseudomonas cichorii ST-24 (FERM BP-2736).

Inventors:
IZUMORI KEN (JP)
TOKUDA MASAAKI (JP)
FLEET GEORGE (GB)
TSUJISAKA YOSHIO (JP)
TAKESHITA KEI (JP)
TSUSAKI KEIJI (JP)
OKUMA KAZUHIRO (JP)
Application Number:
PCT/JP2007/072442
Publication Date:
May 29, 2008
Filing Date:
November 20, 2007
Export Citation:
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Assignee:
UNIV KAGAWA NAT UNIV CORP (JP)
RARE SUGAR PRODUCTION TECHNICA (JP)
FUSHIMI PHARMACEUTICAL CO LTD (JP)
HAYASHIBARA BIOCHEM LAB (JP)
MATSUTANI KAGAKU KOGYO KK (JP)
IZUMORI KEN (JP)
TOKUDA MASAAKI (JP)
FLEET GEORGE (GB)
TSUJISAKA YOSHIO (JP)
TAKESHITA KEI (JP)
TSUSAKI KEIJI (JP)
OKUMA KAZUHIRO (JP)
International Classes:
C12N9/90; C07H3/02; C12P19/24; C12N15/09
Domestic Patent References:
WO2004063369A12004-07-29
WO2004063369A12004-07-29
Foreign References:
JPH06125776A1994-05-10
JPS59500647A1984-04-19
JP2006515883A2006-06-08
JP3333969B22002-10-15
US3333969A1967-08-01
JP2006153591A2006-06-15
JPH0856659A1996-03-05
Other References:
MASAMI M. ET AL.: "New Syntheses of 6-Deoxy-L-gulose and 6-Deoxy-L-talose", CHEM. PHARM. BULL., vol. 34, no. 10, 1986, pages 4037 - 4044, XP003022660
See also references of EP 2161332A4
G.E. EDELMAN, SPEKTRUM WISS, no. 6, 1964, pages 62
V. GINSBURG, ADV. ENZYMOL, vol. 36, 1972, pages 131
G.M.W.COOK; E.W.STODDARD: "Surface carbohydrates of the Eucaryotic Cell", 1973, ACADEMIC PRESS
P. ALBERSHEIM; A.G.DARVILL, SPEKTRUM WISS, no. 11, 1985, pages 86
T.W.RADEMACHER; R.B.PAREKH; R.A.DWEK, ANN. REV. BIOCHEM., vol. 57, 1988, pages 785
MOLECULAR CLONING, vol. 2, 13 March 1989 (1989-03-13)
Attorney, Agent or Firm:
SUDO, Asako et al. (Kajinocho Koganei-shi, Tokyo 02, JP)
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