Title:
DERMAL PAPILLA CELL GROWTH PROMOTER, FIBROBLAST GROWTH FACTOR 7 (FGF-7) PRODUCTION PROMOTER, VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) PRODUCTION PROMOTER, INSULIN-LIKE GROWTH FACTOR 1 (IGF-1) PRODUCTION PROMOTER, HEPATOCYTE GROWTH FACTOR (HGF) PRODUCTION PROMOTER, AND HAIR GROWTH AGENT
Document Type and Number:
WIPO Patent Application WO/2019/004479
Kind Code:
A1
Abstract:
Provided are the following, each of which exhibits a superior effect over the prior art: a novel dermal papilla cell growth promoter; a fibroblast growth factor 7 (FGF-7) production promoter; a vascular endothelial growth factor (VEGF) production promoter; an insulin-like growth factor 1 (IGF-1) production promoter; a hepatocyte growth factor (HGF) production promoter; and a hair growth agent containing at least one of said promoters. The hair growth agent contains at least one of: lanosterol; 3β-hydroxylanosta-8,24-dien-21-al; inotodiol; 3β,21-dihydroxylanosta-8,24-diene; and trametenolic acid as an active ingredient.
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Inventors:
FUKUMOTO TAKATOSHI (JP)
KASHIWADA YOSHIKI (JP)
TANAKA NAONOBU (JP)
SAGAYAMA KAZUMI (JP)
KASHIWADA YOSHIKI (JP)
TANAKA NAONOBU (JP)
SAGAYAMA KAZUMI (JP)
Application Number:
PCT/JP2018/024979
Publication Date:
January 03, 2019
Filing Date:
June 29, 2018
Export Citation:
Assignee:
SVENSON CO LTD (JP)
UNIV TOKUSHIMA (JP)
UNIV TOKUSHIMA (JP)
International Classes:
A61K31/575; A61K8/63; A61K31/56; A61P17/14; A61P43/00; A61Q7/00
Domestic Patent References:
| WO2005079164A2 | 2005-09-01 | |||
| WO2014087960A1 | 2014-06-12 | |||
| WO2006090613A1 | 2006-08-31 |
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Other References:
SZOKA, L. ET AL.: "Acetylenic derivative of betulin induces apoptosis in endometrial adenocarcinoma cell line", BIOMEDICINE AND PHARMACOTHERAPY, vol. 95, September 2017 (2017-09-01), pages 429 - 436, XP085226387
SAGAYAMA, KAZUMI ET AL.: "Research (9) on traditional medicines of Mongolia race - Exploratory research on ''Fuscoporia obliqua'' fruit body-derived active ingredients for hair restoration and hair growth", ABSTRACTS OF ANNUAL CONFERENCE OF THE PHARMACEUTICAL SOCIETY OF JAPAN, vol. 138, March 2018 (2018-03-01)
SAGAYAMA, KAZUMI ET AL.: "Research (9) on traditional medicines of Mongolia race - Exploratory research on ''Fuscoporia obliqua'' fruit body-derived active ingredients for hair restoration and hair growth", ABSTRACTS OF ANNUAL CONFERENCE OF THE PHARMACEUTICAL SOCIETY OF JAPAN, vol. 138, March 2018 (2018-03-01)
Attorney, Agent or Firm:
YOSHIDA Tadanori (JP)
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