Title:
DETECTION METHOD, DETECTION CARD AND DETECTION KIT FOR SARS-COV-2, AND PROTECTIVE MASK
Document Type and Number:
WIPO Patent Application WO/2023/221690
Kind Code:
A1
Abstract:
Provided is a detection method for SARS-CoV-2, which achieves the purpose of detection by preparing a specific indication cell and utilizing the phenomenon of color development or gel formation after a substrate protein synthesized by the indication cell is in contact with an enzyme protein of SARS-CoV-2. In addition, also provided are a virus detection card and a virus detection kit prepared by using the indication cell or the substrate protein component, and a protective mask with virus monitoring functionality. By culturing live viruses, the present invention features increased viral load and improved detection sensitivity, as well as superior detection accuracy to that of antigen detections. In addition, the detection kit also has the advantage of self-testing, which avoids cross-infection during centralized sampling. The protective mask has real-time monitoring capability, which may effectively exert the epidemic control effect.
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Inventors:
ZHANG YUE (CN)
Application Number:
PCT/CN2023/087592
Publication Date:
November 23, 2023
Filing Date:
April 11, 2023
Export Citation:
Assignee:
ZHANG YUE (CN)
International Classes:
C12Q1/70; A41D13/11; C12Q1/37
Domestic Patent References:
| WO2021262734A2 | 2021-12-30 | |||
| WO2021173865A2 | 2021-09-02 |
Foreign References:
| CN215455610U | 2022-01-11 | |||
| US20210301319A1 | 2021-09-30 |
Other References:
FROGGATT HEATHER M, HEATON BROOK E, HEATON NICHOLAS S: "Development of a Fluorescence-Based, High-Throughput SARS-CoV-2 3CL pro Reporter Assay", JOURNAL OF VIROLOGY, UNITED STATES, 27 October 2020 (2020-10-27), United States , pages 1 - 9, XP055844922, DOI: 10.1128/JVI.01265-20
O'BRIEN, A. ET AL.: "Detecting SARS-CoV-2 3CLpro Expression and Activity Using a Polyclonal Antiserum and a Luciferase-Based Biosensor", VIROLOGY, vol. 556, 26 January 2021 (2021-01-26), XP086503489, DOI: 10.1016/j.virol.2021.01.010
O'BRIEN, A. ET AL.: "Detecting SARS-CoV-2 3CLpro Expression and Activity Using a Polyclonal Antiserum and a Luciferase-Based Biosensor", VIROLOGY, vol. 556, 26 January 2021 (2021-01-26), XP086503489, DOI: 10.1016/j.virol.2021.01.010
Attorney, Agent or Firm:
SHENYANG KEWEI PATENT AGENCY CO., LTD (CN)
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