Title:
DETECTION OF PROTEINS FROM CIRCULATING NEOPLASTIC CELLS
Document Type and Number:
WIPO Patent Application WO2007121465
Kind Code:
B1
Abstract:
The protein EGFR, ERCC1, RRM1, thymidylate synthase, or beta-tubulin from cancer cells is detected in a blood sample by enriching the cancer cells from the blood sample followed by performing on the enriched cancer cells an immunoassay capable of detecting the proteins mentioned above. Cancer patients overexpressing EGFR are treated with an anti-EGFR agent, for example cetuximab, panitumumab, erlotinib or gefitinib.
Inventors:
LORENCE ROBERT M (US)
Application Number:
PCT/US2007/066857
Publication Date:
September 12, 2008
Filing Date:
April 18, 2007
Export Citation:
Assignee:
WELLSTAT BIOLOGICS CORP (US)
LORENCE ROBERT M (US)
LORENCE ROBERT M (US)
International Classes:
G01N33/53; G01N33/557; G01N33/574; G01N33/58; G01N33/533; G01N33/534
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