Title:
DEUTERIUM-MODIFIED THIENOPYRIDONE COMPOUND
Document Type and Number:
WIPO Patent Application WO/2022/111517
Kind Code:
A1
Abstract:
A deuterium-modified thienopyridone compound, a preparation method therefor, a pharmaceutical composition thereof, and a medical use thereof. The deuterium-modified thienopyridone compound is shown in formula I, and has been shown to inhibit HPK1 kinase activity, being capable of achieving an anti-tumour effect.
Inventors:
ZHANG YINSHENG (CN)
GAO YONG (CN)
YIN YUAN (CN)
SHI WEI (CN)
ZHAO DAMIN (CN)
ZHU GAOYUAN (CN)
WANG XIAOJIN (CN)
JI YANPENG (CN)
GAO YONG (CN)
YIN YUAN (CN)
SHI WEI (CN)
ZHAO DAMIN (CN)
ZHU GAOYUAN (CN)
WANG XIAOJIN (CN)
JI YANPENG (CN)
Application Number:
PCT/CN2021/132748
Publication Date:
June 02, 2022
Filing Date:
November 24, 2021
Export Citation:
Assignee:
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN)
International Classes:
C07D495/04; A61K31/4365; A61P35/00
Domestic Patent References:
| WO2021226707A1 | 2021-11-18 |
Foreign References:
| CN107922431A | 2018-04-17 | |||
| CN109721620A | 2019-05-07 |
Attorney, Agent or Firm:
BEIJING SANYOU INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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