DEVELOPMENT OF NOVEL DDS TARGETING LYSOSOMES

Title:

DEVELOPMENT OF NOVEL DDS TARGETING LYSOSOMES

Document Type and Number:

WIPO Patent Application WO/2022/145449

Kind Code:

A1

Abstract:

The present invention provides a hydrolase used in enzyme replacement therapy for a lysosomal storage disease.　Provided is a hydrolase that is present in lysosomes and that, when deficient, causes a lysosomal storage disease, the hydrolase including at least one sugar chain having a biantennary sugar chain with a sialic acid at an end.

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Inventors:

ITOH KOHJI (JP)
KINOSHITA TAKASHI (JP)
MITANI AI (JP)

Application Number:

PCT/JP2021/048780

Publication Date:

July 07, 2022

Filing Date:

December 28, 2021

Export Citation:

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Assignee:

UNIV TOKUSHIMA (JP)
FUSHIMI PHARMACEUTICAL CO LTD (JP)

International Classes:

A61K38/47; C12N9/14; A61K38/48; A61P3/00; A61P43/00; C12N9/24; C12N9/64; C12N15/56; C12N15/57

Foreign References:

JP2004502456A	2004-01-29
JP2020010662A	2020-01-23

Other References:

KOJI ITO, ET AL.: "Development of pharmaceuticals for humans and animals using silkworms.", RESEARCH FOR AGRI-HEALTH TRANSLATIONAL RESEARCH PROJECT, AGRIKNOWLEDGE, JAPAN, 1 March 2016 (2016-03-01), Japan, pages 1 - 386, XP055948103, Retrieved from the Internet [retrieved on 20220802]

Attorney, Agent or Firm:

HIRAKI & ASSOCIATES (JP)

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