Title:
DEVICE FOR MEASURING CONCENTRATION OF SUBSTANCE IN BLOOD, AND METHOD FOR MEASURING CONCENTRATION OF SUBSTANCE IN BLOOD
Document Type and Number:
WIPO Patent Application WO/2016/117520
Kind Code:
A1
Abstract:
The present invention measures the concentration of a substance in blood noninvasively, with high accuracy, and using a simple configuration. Laser light 100 generated by a light source 10 is locally radiated into the bodily epithelium (the body) F of a subject, and diffuse reflected light 200 therefrom is detected by a light detector (a light detection unit) 40. The laser light 100 that is used is mid-infrared light, has a wavelength of, for example, 9.26 μm, and is oscillated by the light source 10. The light source 10 generates the laser light 100 by using an OPO (an optical parametric oscillator) 12 to simultaneously lengthen the wavelength of and amplify pulsed excitation light 101 that is oscillated from an excitation-light source 11. An approximately tabular window 30 that is configured from a material that is transparent to mid-infrared light is provided between a light-guiding unit 20 and the bodily epithelium F. The window 30 and the bodily epithelium F are in tight contact. Glucose concentration in interstitial fluid can be calculated using a normalized light intensity that is calculated from the signal ratio between the light detector 40 and a monitor light detector 16.
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Inventors:
YAMAKAWA KOICHI (JP)
Application Number:
PCT/JP2016/051339
Publication Date:
July 28, 2016
Filing Date:
January 19, 2016
Export Citation:
Assignee:
JAPAN ATOMIC ENERGY AGENCY (JP)
International Classes:
A61B5/1455
Domestic Patent References:
| WO2006051778A1 | 2006-05-18 | |||
| WO2014033465A1 | 2014-03-06 | |||
| WO2007141859A1 | 2007-12-13 |
Foreign References:
| JP2008046246A | 2008-02-28 |
Other References:
See also references of EP 3248544A4
Attorney, Agent or Firm:
HORI, Shiroyuki et al. (JP)
Ditch Shiroyuki (JP)
Ditch Shiroyuki (JP)
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