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Title:
DEVICE, METHOD AND COMPUTER READABLE STORAGE MEDIUM FOR QUANTITATIVE PHASE IMAGING
Document Type and Number:
WIPO Patent Application WO/2023/083042
Kind Code:
A1
Abstract:
A device, a method and a computer-readable storage medium for quantitative phase imaging are provided. The method comprises: obtaining a multiplexed interferogram of a sample, where the multiplexed interferogram is an imaging map captured by a camera when a sample beam composed of at least two beams with different wavelengths to illuminate the sample and then penetrate into at least two cubic beam splitters to combine with the at least two beams with different wavelengths as reference beams; and performing a phase retrieval on the multiplexed interferogram to obtain a phase map of the sample at the wavelength of each beam that composes the sample beam. The device is compact and ease-of-use, and can realize versatile measurement functions for more comprehensive studies in biology and material studies.

Inventors:
ZHOU RENJIE (CN)
NIU MENGXUAN (CN)
SUN RUI (CN)
Application Number:
PCT/CN2022/128777
Publication Date:
May 19, 2023
Filing Date:
October 31, 2022
Export Citation:
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Assignee:
BAY JAY RAY TECH LIMITED (CN)
International Classes:
G01N21/45; G01N21/64
Foreign References:
US10488175B22019-11-26
CN112444501A2021-03-05
US20150198795A12015-07-16
CN109804294A2019-05-24
Other References:
"Master's Thesis", 1 May 2014, BEIJING UNIVERSITY OF TECHNOLOGY, CN, article OUYANG, LITING: "Study on Phase Contrast Imaging and the Refractive Index Measurement for Biological Cells by Digital Holographic Microscopy", pages: 1 - 60, XP009545540
GABRIEL POPESCU ET AL: "9.2 Hilbert Phase Microscopy", QUANTITATIVE PHASE IMAGING OF CELLS AND TISSUES, 30 November 2017 (2017-11-30), XP009546221
MATTHEW T. RINEHART, NATAN T. SHAKED, NATHAN J. JENNESS, ROBERT L. CLARK, AND ADAM WAX: "Simultaneous two-wavelength transmission quantitative phase microscopy with a color camera", OPTICS LETTERS, OPTICAL SOCIETY OF AMERICA, US, vol. 35, no. 15, 1 August 2010 (2010-08-01), US , pages 2612 - 2614, XP001556371, ISSN: 0146-9592, DOI: 10.1364/OL.35.002612
HUANG MENG, QIN HONGPENG, JIANG ZHUQING: "Real-time quantitative phase imaging by single-shot dual-wavelength off-axis digital holographic microscopy", APPLIED OPTICS, OPTICAL SOCIETY OF AMERICA, US, vol. 60, no. 15, 20 May 2021 (2021-05-20), US , pages 4418 - 4425, XP093065774, ISSN: 1559-128X, DOI: 10.1364/AO.424666
HAN HAO ET AL: "Unmarked Microscopic Imaging based on Different Light Sources", ACTA LASER BIOLOGY SINICA, 30 April 2018 (2018-04-30), XP009546246
ZHOU HONGXIAN ET AL: "Phase Unwrapping in Spectral Domain Phase Microscopy", ACTA OPTICA SINICA, 28 February 2019 (2019-02-28), XP009546250
Attorney, Agent or Firm:
SHENZHEN ZAN IP AGENCY (CN)
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