Title:
DEVICE AND METHOD FOR SAFE LOCATION AND MARKING OF A CAVITY AND SENTINEL LYMPH NODES
Document Type and Number:
WIPO Patent Application WO2000038579
Kind Code:
B1
Abstract:
Cavity and sentinel lymph node marking devices, marker delivery devices, and methods are disclosed. More particularly, upon insertion into a body, the cavity marking device and method enable one to determine the center, orientation, and periphery of the cavity by radiographic, mammography, echogenic, or other noninvasive imaging techniques. A composition and method are disclosed for locating the sentinel lymph node in a mammalian body to determine if cancerous cells have spread thereto. The composition is preferably a fluid composition consisting of a carrier fluid and some type of contrast agent; alternatively, the contrast agent may itself be a fluid and therefore not need a separate carrier fluid. This composition is capable of (1) deposition in or around a lesion and migration to and accumulation in the associated sentinel node, and (2) remote detection via any number of noninvasive techniques. Also disclosed is a method for remotely detecting the location of a sentinel node by (1) depositing a remotely detectable fluid in or around a lesion for migration to and accumulation in the associated sentinel node and (2) remotely detecting the location of that node with a minimum of trauma and toxicity to the patient. The composition and method may serve to mark a biopsy cavity, as well as mark the sentinel lymph node. The marking methods also may combine any of the features as described with the marking device and delivery device.
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Inventors:
SIRIMANNE D LAKSEN (US)
FAWZI NATALIE V (US)
SUTTON DOUGLAS S (US)
LEBOVIC GAIL S (US)
CONSTON STANLEY R (US)
WILSON PETER M (US)
MORRISSEY ANNE B (US)
BUSH MARY ELIZABETH (US)
FAWZI NATALIE V (US)
SUTTON DOUGLAS S (US)
LEBOVIC GAIL S (US)
CONSTON STANLEY R (US)
WILSON PETER M (US)
MORRISSEY ANNE B (US)
BUSH MARY ELIZABETH (US)
Application Number:
PCT/US1999/030619
Publication Date:
January 18, 2001
Filing Date:
December 23, 1999
Export Citation:
Assignee:
VIVANT MEDICAL INC (US)
SIRIMANNE D LAKSEN (US)
FAWZI NATALIE V (US)
SUTTON DOUGLAS S (US)
LEBOVIC GAIL S (US)
CONSTON STANLEY R (US)
WILSON PETER M (US)
MORRISSEY ANNE B (US)
BUSH MARY ELIZABETH (US)
SIRIMANNE D LAKSEN (US)
FAWZI NATALIE V (US)
SUTTON DOUGLAS S (US)
LEBOVIC GAIL S (US)
CONSTON STANLEY R (US)
WILSON PETER M (US)
MORRISSEY ANNE B (US)
BUSH MARY ELIZABETH (US)
International Classes:
A61B19/00; A61K49/00; A61B17/00; (IPC1-7): A61B17/00; A61B8/00; A61B19/00
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