Title:
DEVICE, METHODS AND SPONGES FOR IONTOPHORETIC DRUG DELIVERY
Document Type and Number:
WIPO Patent Application WO2004073794
Kind Code:
A3
Abstract:
Disclosed are devices and methods for administration of charged drugs to tissues of the oral cavity and for intra-tissue administration. The disclosed drug applicator for intra-tissue use includes an introducer such as a needle or catheter that is adapted to penetrate into a living tissue. The introducer has a drug-providing portion, and the applicator has current-generating element to pass through it an electrical current. Passing an electrical current through the drug-providing portion causes the drug to eject into treated tissue. Also disclosed are charged drugs suitable for iontophoretic administration, which include a bioactive agent encapsulated in charged nano-particles.
More Like This:
Inventors:
DOMB ABRAHAM J (IL)
Application Number:
PCT/IL2004/000167
Publication Date:
November 25, 2004
Filing Date:
February 19, 2004
Export Citation:
Assignee:
YISSUM RES DEV CO (IL)
DOMB ABRAHAM J (IL)
DOMB ABRAHAM J (IL)
International Classes:
A61N1/30; (IPC1-7): A61N1/30; A61K9/51
Domestic Patent References:
| WO2001012260A1 | 2001-02-22 | |||
| WO1997004832A1 | 1997-02-13 | |||
| WO1999040967A1 | 1999-08-19 | |||
| WO1994005361A1 | 1994-03-17 |
Foreign References:
| US20020183685A1 | 2002-12-05 | |||
| US6048545A | 2000-04-11 | |||
| US5833647A | 1998-11-10 | |||
| EP0774272A1 | 1997-05-21 |
Other References:
NICOLI S. ET AL.: "Design of triptorelin loaded nanospheres for transdermal iontophoretic administration", INT. J. OF PHARMACEUTICS, vol. 214, 2001, pages 31 - 35, XP002285730
Download PDF: