Title:
DEVICES AND METHODS FOR USING CENTRIPETAL ACCELERATION TO DRIVE FLUID MOVEMENT IN A MICROFLUIDICS SYSTEM
Document Type and Number:
WIPO Patent Application WO1998053311
Kind Code:
A9
Abstract:
This invention provides methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. Specifically, the invention provides a microsystem platform for use with a micromanipulation device to manipulate the platform by rotation, thereby utilizing the centripetal force resulting from rotation of the platform to motivate fluid movement through microchannels embedded in the microplatform. The microsystem platforms of the invention are also provided having microfluidics components, resistive heating elements, temperature sensing elements, mixing structures, capillary and sacrificial valves, and methods for using these microsystems platforms for performing biological, enzymatic, immunological and chemical assays. An electronic spindle designed rotor capable of transferring electrical signals to and from the microsystem platforms of the invention is also provided.
Inventors:
KELLOGG GREGORY
KIEFFER-HIGGINS STEPHEN G
CARVALHO BRUCE L
DAVIS GENE A
WILLIS JOHN P
MINIOR TED
CHAPMAN LAURA L
KOB MIKAYLA
OELTJEN SARAH D
OMMERT SHARI
MIAN ALEC
KIEFFER-HIGGINS STEPHEN G
CARVALHO BRUCE L
DAVIS GENE A
WILLIS JOHN P
MINIOR TED
CHAPMAN LAURA L
KOB MIKAYLA
OELTJEN SARAH D
OMMERT SHARI
MIAN ALEC
Application Number:
PCT/US1998/010520
Publication Date:
April 22, 1999
Filing Date:
May 22, 1998
Export Citation:
Assignee:
GAMERA BIOSCIENCE CORP (US)
International Classes:
B01F13/00; B01L3/00; B01L7/00; B81B1/00; G01N33/48; B81B7/04; F16K13/10; F16K31/00; G01N1/10; G01N21/07; G01N31/20; G01N33/483; G01N35/00; G01N37/00; H01C17/06; H01C17/065; H01R39/64; B01L9/00; (IPC1-7): G01N21/07; F16K31/00; F16K13/10; H01C17/065; H01R39/64
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