Title:
DIAGNOSIS AND TREATMENT OF CEREBRAL MALARIA
Document Type and Number:
WIPO Patent Application WO/2015/147335
Kind Code:
A1
Abstract:
The present invention relates to a cerebral malaria marker and techniques for the application thereof. A marker for identifying cerebral malaria, said marker being based on the state of olfactory bulb or comprising a factor in the CCL21-CXCR3-CCR7 signal transduction system such as CCL21, CXCR3 or CCR7 or an expression product thereof, a fragment thereof or a derivative thereof; a detection agent for identifying cerebral malaria, said detection agent comprising a substance binding to a factor in the CCL21-CXCR3-CCR7 signal transduction system such as CCL21, CXCR3 or CCR7 or an expression product thereof; and a medicinal composition for preventing or treating cerebral malaria, said medicinal composition comprising an inhibitor of a factor in the CCL21-CXCR3-CCR7 signal transduction system such as CCL21, CXCR3 or CCR7.
Inventors:
COBAN CEVAYIR (JP)
YOSHIOKA YOSHICHIKA (JP)
ISHII KEN (JP)
AOSHI TAIKI (JP)
YOSHIOKA YOSHICHIKA (JP)
ISHII KEN (JP)
AOSHI TAIKI (JP)
Application Number:
PCT/JP2015/060403
Publication Date:
October 01, 2015
Filing Date:
March 26, 2015
Export Citation:
Assignee:
UNIV OSAKA (JP)
NAT INST OF BIOMEDICAL INNOVATION HEALTH AND NUTRITION (JP)
NAT INST OF BIOMEDICAL INNOVATION HEALTH AND NUTRITION (JP)
International Classes:
A61B5/055; A61B10/00; A61K39/395; A61P33/06; C07K14/47; C07K16/18; C12N15/09; C12Q1/68; G01N33/53
Domestic Patent References:
| WO2012165295A1 | 2012-12-06 | |||
| WO2003072134A1 | 2003-09-04 |
Foreign References:
| JP2012507546A | 2012-03-29 | |||
| JP2009528977A | 2009-08-13 | |||
| JP2008545000A | 2008-12-11 | |||
| JP2004517078A | 2004-06-10 |
Attorney, Agent or Firm:
YAMAMOTO, Shusaku et al. (JP)
Shusaku Yamamoto (JP)
Shusaku Yamamoto (JP)
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