Title:
DIAZASPIROALKANE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2010/123018
Kind Code:
A1
Abstract:
Disclosed is a diazaspiroalkane derivative represented by general formula (II) [wherein R11, R12 and R13 independently represent a hydrogen atom, a halogen atom, a C1-8 alkyl group, a C1-8 alkoxy group, a C1-8 alkyl group which is substituted by 1 to 3 halogen atoms, a C1-8 alkylsulfonyl group, or the like; T1, U1, V1 and W1 independently represent a bond or a C1-5 alkylene group which may have a substituent; B1 represents C(=O), a C1-5 alkylene group which may have a substituent, or the like; Y1 and Z1 independently represent a C1-3 alkylene group which may have a substituent; and R represents a C1-8 alkyl group, or the like], which is a GPR119 agonist, or a pharmaceutically acceptable salt thereof. The diazaspiroalkane derivative or the pharmaceutically acceptable salt thereof can be used as a therapeutic agent for diabetes.
Inventors:
ENDO TSUYOSHI (JP)
TAKAHASHI RIE (JP)
TANAKA HIROTO (JP)
KUNIGAMI TOSHIHIRO (JP)
TAKAHASHI RIE (JP)
TANAKA HIROTO (JP)
KUNIGAMI TOSHIHIRO (JP)
Application Number:
PCT/JP2010/057036
Publication Date:
October 28, 2010
Filing Date:
April 21, 2010
Export Citation:
Assignee:
NIPPON CHEMIPHAR CO (JP)
ENDO TSUYOSHI (JP)
TAKAHASHI RIE (JP)
TANAKA HIROTO (JP)
KUNIGAMI TOSHIHIRO (JP)
ENDO TSUYOSHI (JP)
TAKAHASHI RIE (JP)
TANAKA HIROTO (JP)
KUNIGAMI TOSHIHIRO (JP)
International Classes:
C07D487/10; A61K31/4523; A61K31/4545; A61P3/10; A61P43/00
Domestic Patent References:
| WO2008033460A2 | 2008-03-20 | |||
| WO2008008887A2 | 2008-01-17 | |||
| WO2007016496A2 | 2007-02-08 | |||
| WO2006053024A2 | 2006-05-18 | |||
| WO2001030780A2 | 2001-05-03 |
Attorney, Agent or Firm:
Chigusa, Shinichi (JP)
1000 Shin-ichi Kusa (JP)
1000 Shin-ichi Kusa (JP)
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