Title:
DIAZEPINEDIONE DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/2010/090300
Kind Code:
A1
Abstract:
Diazepinedione derivatives represented by general formula (I) or pharmacologically acceptable salts thereof are used as P2X4 receptor antagonist. In general formula (I), R1 represents a hydrogen atom, a C1-8 alkyl group, or the like; R2 represents a hydrogen atom, a C1-8 alkyl group, a C1-8 alkoxy group, a mono-, di-, or tri-halogenated C1-8 alkyl group, a halogen atom, a hydroxyl group, a nitro group, an amino group, a carboxyl group, a cyano group, or the like; R3 represents a hydrogen atom, a C1-8 alkyl group, or the like; and R4 and R5 may be the same or different and each represents a hydrogen atom, a C1-8 alkyl group, or the like.
More Like This:
| JP2003137896 | INTERLEUKIN-1β CONVERTING ENZYME INHIBITOR |
| JP2009519938 | (R)-Method of isolating tofisopam |
| JP2009057281 | P2X4 RECEPTOR ANTAGONIST |
Inventors:
SAKUMA SHOGO (JP)
ENDO TSUYOSHI (JP)
TAKAHASHI TOSHIHIRO (JP)
IMAI TOSHIYASU (JP)
TSUDA MAKOTO (JP)
INOUE KAZUHIDE (JP)
ENDO TSUYOSHI (JP)
TAKAHASHI TOSHIHIRO (JP)
IMAI TOSHIYASU (JP)
TSUDA MAKOTO (JP)
INOUE KAZUHIDE (JP)
Application Number:
PCT/JP2010/051740
Publication Date:
August 12, 2010
Filing Date:
February 02, 2010
Export Citation:
Assignee:
NIPPON CHEMIPHAR CO (JP)
SAKUMA SHOGO (JP)
ENDO TSUYOSHI (JP)
TAKAHASHI TOSHIHIRO (JP)
IMAI TOSHIYASU (JP)
TSUDA MAKOTO (JP)
INOUE KAZUHIDE (JP)
SAKUMA SHOGO (JP)
ENDO TSUYOSHI (JP)
TAKAHASHI TOSHIHIRO (JP)
IMAI TOSHIYASU (JP)
TSUDA MAKOTO (JP)
INOUE KAZUHIDE (JP)
International Classes:
C07D243/10; A61K31/551; A61P25/04; A61P43/00
Domestic Patent References:
| WO2008023847A1 | 2008-02-28 | |||
| WO2007072974A1 | 2007-06-28 | |||
| WO2003051274A2 | 2003-06-26 |
Attorney, Agent or Firm:
Chigusa, Shinichi (JP)
1000 Shin-ichi Kusa (JP)
1000 Shin-ichi Kusa (JP)
Download PDF: