Title:
DIHYDROIMIDAZO-PYRIMIDINONE COMPOUNDS AS LP-PLA2 INHIBITORS AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/027116
Kind Code:
A1
Abstract:
Provided are compounds of Formula (I) or a pharmaceutically acceptable salt or solvate thereof, wherein R1, R2, R3, R4, Q, n, and A are described herein, which are useful as Lp-PLA2 inhibitors, pharmaceutical compositions comprising the same, and use thereof in the treatment of Lp-PLA2-associated diseases or conditions.
Inventors:
GUAN XIAOMING (CN)
LV CHEN (CN)
ZHAI DONGXU (CN)
ZHANG XIAOYU (CN)
LIU JIE (CN)
LV CHEN (CN)
ZHAI DONGXU (CN)
ZHANG XIAOYU (CN)
LIU JIE (CN)
Application Number:
PCT/CN2023/073385
Publication Date:
February 08, 2024
Filing Date:
January 20, 2023
Export Citation:
Assignee:
4B TECH BEIJING CO LIMITED (CN)
International Classes:
C07D471/18; A61K31/519; A61K31/527; A61P3/10; A61P9/10; A61P25/16; A61P25/28; A61P27/00; C07D487/14; C07D487/20
Domestic Patent References:
| WO2021089032A1 | 2021-05-14 | |||
| WO2016011930A1 | 2016-01-28 | |||
| WO2013013503A1 | 2013-01-31 | |||
| WO2014114694A1 | 2014-07-31 | |||
| WO2016012916A1 | 2016-01-28 | |||
| WO2021063145A1 | 2021-04-08 |
Foreign References:
| CN114057740A | 2022-02-18 |
Attorney, Agent or Firm:
CHENG & PENG INTELLECTUAL PROPERTY LAW OFFICE (CN)
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