Title:
DIRECT PRODUCTION OF SIRNAS IN SACCHAROMYCES BOULARDII AND PACKAGING IN EXTRACELLULAR VESICLES (EVS) FOR TARGETED GENE SILENCING
Document Type and Number:
WIPO Patent Application WO/2023/183794
Kind Code:
A9
Abstract:
The present invention is direct to the direct expression of siRNA molecules in yeast, which can be packaged into extracellular vesicles (EVs) and delivered to a target organism causing the downregulation of a select gene.
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Inventors:
VINOGRADOVA-SHAH TATIANA (US)
SAYRE RICHARD T (US)
PERTZEV ALEX (US)
KRUCKEBERG ARLE (US)
SAYRE RICHARD T (US)
PERTZEV ALEX (US)
KRUCKEBERG ARLE (US)
Application Number:
PCT/US2023/064756
Publication Date:
February 01, 2024
Filing Date:
March 21, 2023
Export Citation:
Assignee:
MERCURY BIO INC (US)
International Classes:
A61K48/00; A61K9/127; C12N15/113; C12N15/81
Attorney, Agent or Firm:
KERR, David S. (US)
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