Title:
DISINFECTANT AND ANTIMICROBIAL COMPOSITIONS, IN PARTICULAR FOR THE VETERINARY FIELD
Document Type and Number:
WIPO Patent Application WO/2015/198265
Kind Code:
A3
Abstract:
There are described compositions comprising chlorhexidine or a salt thereof and at least one peptide, and their use in the treatment of infections caused by bacteria, fungi and/or yeasts, in particular in the veterinary field.
Inventors:
CABASSI CLOTILDE SILVIA (IT)
FALANGA GENNARO (IT)
ROMANI ANTONELLO (IT)
FALANGA GENNARO (IT)
ROMANI ANTONELLO (IT)
Application Number:
PCT/IB2015/054790
Publication Date:
March 03, 2016
Filing Date:
June 25, 2015
Export Citation:
Assignee:
ICF SRL (IT)
International Classes:
A61K38/10; A61K31/155; A61K38/12; A61K38/16; A61K38/17; A61K38/40; A61L12/14; A61P31/04; A61P31/10; A61P31/12
Domestic Patent References:
| WO2009037183A2 | 2009-03-26 |
Foreign References:
| US20070003538A1 | 2007-01-04 |
Other References:
A. A. ROMANI ET AL: "In vitro activity of novel in silico -developed antimicrobial peptides against a panel of bacterial pathogens", JOURNAL OF PEPTIDE SCIENCE, vol. 19, no. 9, 26 September 2013 (2013-09-26), pages 554 - 565, XP055119521, ISSN: 1075-2617, DOI: 10.1002/psc.2532
GIUSEPPANTONIO MAISETTA ET AL: "Activity of Human ss-Defensin 3 Alone or Combined with Other Antimicrobial Agents against Oral Bacteria", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, AMERICAN SOCIETY FOR MICROBIOLOGY, vol. 47, no. 10, 1 October 2003 (2003-10-01), pages 3349 - 3351, XP008130454, ISSN: 0066-4804, DOI: 10.1128/AAC.47.10.3349-3351.2003
KIM S S ET AL: "SYNERGISTIC INHIBITORY EFFECT OF CATIONIC PEPTIDES AND ANTIMICROBIAL AGENTS ON THE GROWTH OF ORAL STREPTOCOCCI", CARIES RESEARCH, S. KARGER AG, BASEL, CH, vol. 37, 1 January 2003 (2003-01-01), pages 425 - 430, XP008074671, ISSN: 0008-6568, DOI: 10.1159/000073394
REICHEL M ET AL: "Skin bacteria after chlorhexidine exposure-is there a difference in response to human [beta]-Defensin-3?", EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, SPRINGER, BERLIN, DE, vol. 29, no. 6, 27 March 2010 (2010-03-27), pages 623 - 632, XP019807529, ISSN: 1435-4373
KEUN-HYEUNG LEE ET AL: "Antimicrobial activity and conformation of gaegurin-6 amide and its analogs", PEPTIDES, vol. 19, no. 10, 1 January 1998 (1998-01-01), pages 1653 - 1658, XP055168825, ISSN: 0196-9781, DOI: 10.1016/S0196-9781(98)00119-3
PUSATERI C R ET AL: "Sensitivity of Candida albicans biofilm cells grown on denture acrylic to antifungal proteins and chlorhexidine", ARCHIVES OF ORAL BIOLOGY, PERGAMON PRESS, OXFORD, GB, vol. 54, no. 6, 1 June 2009 (2009-06-01), pages 588 - 594, XP026128396, ISSN: 0003-9969, [retrieved on 20090227], DOI: 10.1016/J.ARCHORALBIO.2009.01.016
ANDRÉ C. AMARAL ET AL: "Predicting antimicrobial peptides from eukaryotic genomes: In silico strategies to develop antibiotics", PEPTIDES, vol. 37, no. 2, 1 October 2012 (2012-10-01), pages 301 - 308, XP055217886, ISSN: 0196-9781, DOI: 10.1016/j.peptides.2012.07.021
GIUSEPPANTONIO MAISETTA ET AL: "Activity of Human ss-Defensin 3 Alone or Combined with Other Antimicrobial Agents against Oral Bacteria", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, AMERICAN SOCIETY FOR MICROBIOLOGY, vol. 47, no. 10, 1 October 2003 (2003-10-01), pages 3349 - 3351, XP008130454, ISSN: 0066-4804, DOI: 10.1128/AAC.47.10.3349-3351.2003
KIM S S ET AL: "SYNERGISTIC INHIBITORY EFFECT OF CATIONIC PEPTIDES AND ANTIMICROBIAL AGENTS ON THE GROWTH OF ORAL STREPTOCOCCI", CARIES RESEARCH, S. KARGER AG, BASEL, CH, vol. 37, 1 January 2003 (2003-01-01), pages 425 - 430, XP008074671, ISSN: 0008-6568, DOI: 10.1159/000073394
REICHEL M ET AL: "Skin bacteria after chlorhexidine exposure-is there a difference in response to human [beta]-Defensin-3?", EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, SPRINGER, BERLIN, DE, vol. 29, no. 6, 27 March 2010 (2010-03-27), pages 623 - 632, XP019807529, ISSN: 1435-4373
KEUN-HYEUNG LEE ET AL: "Antimicrobial activity and conformation of gaegurin-6 amide and its analogs", PEPTIDES, vol. 19, no. 10, 1 January 1998 (1998-01-01), pages 1653 - 1658, XP055168825, ISSN: 0196-9781, DOI: 10.1016/S0196-9781(98)00119-3
PUSATERI C R ET AL: "Sensitivity of Candida albicans biofilm cells grown on denture acrylic to antifungal proteins and chlorhexidine", ARCHIVES OF ORAL BIOLOGY, PERGAMON PRESS, OXFORD, GB, vol. 54, no. 6, 1 June 2009 (2009-06-01), pages 588 - 594, XP026128396, ISSN: 0003-9969, [retrieved on 20090227], DOI: 10.1016/J.ARCHORALBIO.2009.01.016
ANDRÉ C. AMARAL ET AL: "Predicting antimicrobial peptides from eukaryotic genomes: In silico strategies to develop antibiotics", PEPTIDES, vol. 37, no. 2, 1 October 2012 (2012-10-01), pages 301 - 308, XP055217886, ISSN: 0196-9781, DOI: 10.1016/j.peptides.2012.07.021
Attorney, Agent or Firm:
ADV IP SRL (via Conservatorio 22, Milano, IT)
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