Title:
DNA DETECTION APPARATUS, DNA DETECTION DEVICE AND DNA DETECTION METHOD
Document Type and Number:
WIPO Patent Application WO/2010/026950
Kind Code:
A1
Abstract:
Provided is a chemical luminescence-detecting apparatus that comprises a plate wherein a plurality of reaction cells are arranged one-dimensionally or two-dimensionally. By simultaneously filling the reaction cells with an enzyme embedded in a gel and with DNA-fixed beads, large amounts of enzyme are trapped in the reaction cells, enzyme activity is improved, and highly sensitive pyrosequencing is realized.
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Inventors:
SHIRAI MASATAKA (JP)
KAJIYAMA TOMOHARU (JP)
KAMBARA HIDEKI (JP)
KAJIYAMA TOMOHARU (JP)
KAMBARA HIDEKI (JP)
Application Number:
PCT/JP2009/065205
Publication Date:
March 11, 2010
Filing Date:
August 31, 2009
Export Citation:
Assignee:
HITACHI LTD (JP)
SHIRAI MASATAKA (JP)
KAJIYAMA TOMOHARU (JP)
KAMBARA HIDEKI (JP)
SHIRAI MASATAKA (JP)
KAJIYAMA TOMOHARU (JP)
KAMBARA HIDEKI (JP)
International Classes:
C12M1/00; C12Q1/68; G01N21/76; G01N33/53; G01N33/543; C12N15/09
Foreign References:
| JP2005505748A | 2005-02-24 | |||
| JP2001238662A | 2001-09-04 | |||
| JP2005520484A | 2005-07-14 | |||
| JP2001506864A | 2001-05-29 |
Other References:
ITO Y. ET AL.: "Photo-reactive polyvinylalcohol for photo-immobilized microarray.", BIOMATERIALS, vol. 26, 2005, pages 211 - 216
OHYAMA K. ET AL.: "A photo-immobilized allergen microarray for screening of allergen-specific", IGE., ALLERGOL. INT., vol. 54, 2005, pages 627 - 631
NAQVI A. ET AL.: "Photochemical immobilization of proteins on microwave- synthesized photoreactive polymers.", ANAL. BIOCHEM., vol. 327, no. 1, 2004, pages 68 - 73
BHAT V.T. ET AL.: "A photochemical method for immobilization of azidated dextran onto aminated poly(ethylene terephthalate) surfaces.", POLYM. INT., vol. 57, January 2008 (2008-01-01), pages 124 - 132
MARGULIES M. ET AL.: "Genome sequencing in microfabricated high-density picolitre reactors.", NATURE, vol. 437, 2005, pages 376 - 380
REVZIN A. ET AL.: "Surface engineering with poly(ethylene glycol) photolithography to create high-density cell arrays on glass.", LANGMUIR, vol. 19, 2003, pages 9855 - 9862
HAHN M.S. ET AL.: "Photolithographic patterning of polyethylene glycol hydrogels.", BIOMATERIALS, vol. 27, 2006, pages 2519 - 2524
OHYAMA K. ET AL.: "A photo-immobilized allergen microarray for screening of allergen-specific", IGE., ALLERGOL. INT., vol. 54, 2005, pages 627 - 631
NAQVI A. ET AL.: "Photochemical immobilization of proteins on microwave- synthesized photoreactive polymers.", ANAL. BIOCHEM., vol. 327, no. 1, 2004, pages 68 - 73
BHAT V.T. ET AL.: "A photochemical method for immobilization of azidated dextran onto aminated poly(ethylene terephthalate) surfaces.", POLYM. INT., vol. 57, January 2008 (2008-01-01), pages 124 - 132
MARGULIES M. ET AL.: "Genome sequencing in microfabricated high-density picolitre reactors.", NATURE, vol. 437, 2005, pages 376 - 380
REVZIN A. ET AL.: "Surface engineering with poly(ethylene glycol) photolithography to create high-density cell arrays on glass.", LANGMUIR, vol. 19, 2003, pages 9855 - 9862
HAHN M.S. ET AL.: "Photolithographic patterning of polyethylene glycol hydrogels.", BIOMATERIALS, vol. 27, 2006, pages 2519 - 2524
Attorney, Agent or Firm:
TSUTSUI, YAMATO (JP)
Tsutsui Daiwa (JP)
Tsutsui Daiwa (JP)
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