Title:
DO3A-BASED ANTITHROMBOTIC AGENT OR HEMOLYTIC AGENT CONTAINING GADOLINIUM COMPLEX
Document Type and Number:
WIPO Patent Application WO/2023/214713
Kind Code:
A1
Abstract:
Disclosed is applicability in novel uses of a DO3A-based material containing a gadolinium complex as an antithrombotic agent or a coagulant, on the basis of a discovery finding that the DO3A-based material containing the gadolinium complex which has been used as an anti-inflammatory agent has a novel effect of suppressing a thrombus induced by thrombin or dissolving blood, without being involved in the function of platelet action which stops bleeding at a damaged or injured area.
Inventors:
CHANG SHA JOUNG (KR)
KIM YEOUN HEE (KR)
CHOI GA RAM (KR)
PARK HYUN JIN (KR)
KIM YE SL (KR)
CHOI MIN JIN (KR)
KIM YEOUN HEE (KR)
CHOI GA RAM (KR)
PARK HYUN JIN (KR)
KIM YE SL (KR)
CHOI MIN JIN (KR)
Application Number:
PCT/KR2023/005214
Publication Date:
November 09, 2023
Filing Date:
April 18, 2023
Export Citation:
Assignee:
ETNOVA THERAPEUTICS CORP (KR)
International Classes:
A61K31/555; A61P7/02; A61P29/00
Foreign References:
| KR20190111768A | 2019-10-02 | |||
| US20110092806A1 | 2011-04-21 | |||
| KR20220037067A | 2022-03-24 | |||
| KR20190111376A | 2019-10-02 |
Other References:
ARTHUR HO-HON LEUNG, JIEFU JIN, SHUXIA WANG, HAO LEI, WING-TAK WONG: "Inflammation Targeted Gd 3+ -Based MRI Contrast Agents Imaging Tumor and Rheumatoid Arthritis Models", BIOCONJUGATE CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 25, no. 6, 18 June 2014 (2014-06-18), US , pages 1112 - 1123, XP055637370, ISSN: 1043-1802, DOI: 10.1021/bc5001356
Attorney, Agent or Firm:
NAM, Gun Pil et al. (KR)
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