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Title:
DOSING REGIMENS
Document Type and Number:
WIPO Patent Application WO/2017/062879
Kind Code:
A3
Abstract:
In some aspects, the present invention provides cell-reactive compstatin analogs and compositions comprising cell-reactive compstatin analogs. In some aspects, the invention further provides methods of using cell-reactive compstatin analogs, e.g., treat a complement-mediated disorder, e.g., to inhibit complement-mediated damage to a cell, tissue, or organ. In some aspects, the invention provides long-acting compstatin analogs and compositions comprising long-acting compstatin analogs. In some aspects, the invention further provides methods of using long-acting compstatin analogs, e.g., to treat a complement-mediated disorder, e.g., to inhibit complement-mediated damage to a cell, tissue, or organ. In some aspects, the invention provides targeted compstatin analogs and compositions comprising targeted compstatin analogs. In some aspects, the invention further provides methods of using targeted compstatin analogs, e.g., to treat a complement-mediated disorder, e.g., to inhibit complement-mediated damage to a cell, tissue, or organ.

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Inventors:
GROSSI FEDERICO (US)
DESCHATELETS PASCAL (US)
FRANCOIS CEDRIC (US)
Application Number:
PCT/US2016/056144
Publication Date:
June 22, 2017
Filing Date:
October 07, 2016
Export Citation:
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Assignee:
APELLIS PHARMACEUTICALS INC (US)
International Classes:
C07K7/06; A61K38/04; A61K38/12; C07K7/50; C07K7/64; C07K14/47
Domestic Patent References:
WO2014152391A12014-09-25
WO2012155107A12012-11-15
Other References:
VIEGAS, TX ET AL.: "Polyoxazoline: Chemistry, Properties, and Applications in Drug Delivery", BIOCONJUGATE CHEMISTRY, vol. 22, no. 5, 20 April 2011 (2011-04-20), pages 976 - 986, XP055082338, DOI: doi:10.1021/bc200049d
Attorney, Agent or Firm:
NGUYEN, Suzanne P. et al. (US)
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