DP2 ANTAGONIST AND USES THEREOF - AMIRA PHARMACEUTICALS INC

Title:

DP2 ANTAGONIST AND USES THEREOF

Document Type and Number:

WIPO Patent Application WO/2011/017201

Kind Code:

A3

Abstract:

Described herein is the DP2 antagonist [2'-(3-benzyl-1-ethyl-ureidomethyl)-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl]-acetic acid, or a pharmaceutically acceptable salt thereof. Also described are methods of preparing the DP2 antagonist, or a pharmaceutically acceptable salt thereof. Also described herein are pharmaceutical compositions suitable for administration to a mammal that include the DP2 antagonist, or a pharmaceutically acceptable salt thereof, and methods of using such pharmaceutical compositions for treating respiratory diseases or conditions, allergic diseases or conditions, inflammatory diseases or conditions, as well as other prostaglandin D2-dependent or prostaglandin D2-mediated diseases or conditions.

Inventors:

STEARNS BRIAN ANDREW (US)
KING CHRISTOPHER DAVID (US)
BRITTAIN JASON EDWARD (US)
HOLME KEVIN ROSS (US)

Application Number:

PCT/US2010/043783

Publication Date:

June 16, 2011

Filing Date:

July 29, 2010

Export Citation:

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Assignee:

AMIRA PHARMACEUTICALS INC (US)
STEARNS BRIAN ANDREW (US)
KING CHRISTOPHER DAVID (US)
BRITTAIN JASON EDWARD (US)
HOLME KEVIN ROSS (US)

International Classes:

C07C275/24; A61K31/17; A61P11/00; C07C273/02; C07C275/16

Domestic Patent References:

WO2005100298A1	2005-10-27
WO2011014587A2	2011-02-03
WO2009099901A1	2009-08-13

Foreign References:

US20020198251A1	2002-12-26
US5239084A	1993-08-24

Other References: