DRUG COAT LAYER AND MEDICAL INSTRUMENT INCLUDING SAME

WIPO Patent Application WO/2013/146381

A1

Provided is a drug coat layer that makes it possible to prevent a drug coated on a medical instrument from peeling and falling off during an operation in which the instrument is passed through a body cavity such as a blood vessel to deliver the drug into the body. The drug coat layer has two modes. The first mode has a phenol compound layer in the bottom layer and, as separate layers in the top layer, a coating layer containing hyaluronic acids (at least one compound selected from the group consisting of hyaluronic acid, alkanoylated hyaluronic acids in which at least some of the hydrogen atoms of the hydroxy groups have been substituted with alkanoyl groups, and salts thereof) and a water-insoluble drug layer. The second mode has a coating layer that contains a hyaluronic acids and a water-insoluble drug. Also provided is a medical instrument using the same.

ISOZAKI MASASHI (JP)
TERAJIMA YOKO (JP)
ANZAI TAKAO (JP)

PCT/JP2013/057504

October 03, 2013

March 15, 2013

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TERUMO CORP (JP)

A61L31/00; A61L29/00

JP2008514380A	2008-05-08
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JP2004123785A	2004-04-22
JPH06508169A	1994-09-14
JP2000507930A	2000-06-27
JP2008517725A	2008-05-29

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WATANABE Mochitoshi et al. (JP)
Mochitoshi Watanabe (JP)

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