Title:
DRUG CONCENTRATION FROM AN ORAL FLUID
Document Type and Number:
WIPO Patent Application WO/2014/176167
Kind Code:
A3
Abstract:
Oral fluid for drug testing has several advantages over other specimens: (1) It may be collected noninvasively and under direct supervision; (2) its drug concentration reflects blood-drug concentrations; and (3) it can be processed by conventional drug screening and confirmation methods. This technology provides a system that measures the quantity of a drug (without needing a priori knowledge of the drug) in an oral fluid specimen and translates this level to a blood plasma drug concentration. The method first measures the concentration of a drug in an oral fluid sample. Next, a processor calculates the blood plasma concentration from the measured oral fluid drug concentration. Finally, this blood plasma drug level is utilized to calculate a total body drug concentration.
Inventors:
STRIPP RICHARD (US)
Application Number:
PCT/US2014/034810
Publication Date:
December 31, 2014
Filing Date:
April 21, 2014
Export Citation:
Assignee:
STERLING HEALTHCARE OPCO LLC (US)
International Classes:
G01N33/50; G01N21/80; G01N33/84
Foreign References:
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| US5968746A | 1999-10-19 | |||
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| US5010473A | 1991-04-23 | |||
| US20080318322A1 | 2008-12-25 | |||
| US20070106138A1 | 2007-05-10 | |||
| US8273305B2 | 2012-09-25 | |||
| US5714341A | 1998-02-03 | |||
| US4900666A | 1990-02-13 |
Other References:
DIPIRO, JT ET AL.: "Concepts in Clinical Pharmacokinetics", 2005, XP055288190, Retrieved from the Internet [retrieved on 20140725]
"Blood Analysis for Compliance Testing", AIT LABORATORIES., 23 June 2011 (2011-06-23), XP055288207, Retrieved from the Internet [retrieved on 20140725]
"Blood Analysis for Compliance Testing", AIT LABORATORIES., 23 June 2011 (2011-06-23), XP055288207, Retrieved from the Internet
Attorney, Agent or Firm:
KINNEAR, Brian et al. (P.O. Box 1247Seattle, WA, US)
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