Title:
DRUG FOR REMOVING AGED CELLS
Document Type and Number:
WIPO Patent Application WO/2018/043463
Kind Code:
A1
Abstract:
Provided is a drug for removing aged cells or a medicinal composition therefor, said drug or composition comprising an SGLT2 inhibitor.
Inventors:
MINAMINO TOHRU (JP)
Application Number:
PCT/JP2017/030867
Publication Date:
March 08, 2018
Filing Date:
August 29, 2017
Export Citation:
Assignee:
UNIV NIIGATA (JP)
MITSUBISHI TANABE PHARMA CORP (JP)
MITSUBISHI TANABE PHARMA CORP (JP)
International Classes:
A61K45/00; A61P43/00
Foreign References:
| JP2016167679A | 2016-09-15 |
Other References:
KEIICHI, IMAMURA: "Kaisetsu SGLT2 Sogaiyaku no Shiyoho", THE JOURNAL OF JAPAN PHYSICIANS ASSOCIATION KAISHI, vol. 30, no. 5, March 2016 (2016-03-01), pages 600 - 607, XP009515442, ISSN: 0914-9627
ATSUSHI OBATA ET AL.: "Tokushu 2-gata Tonyobyo no Atarashii Chiryo Senryaku: Shinki Tonyobyo Chiryoyaku o do Katsuyo suru? I.SGLT2 Sogaiyaku no Tonyobyo Chiryo ni Okeru Senryakuteki Ichizuke Tekishita Kanjazo", TEKISANAI KANJAZO, DIABETES, vol. 7, no. 6, 2015, pages 26 - 34, XP009518399, ISBN: 978-4-287-82072-8
IZUMI HIRATSUKA ET AL.: "Jicchi Ika no Tameno Kokarei Igaku no Rinsho Seminor Shinpo shita Anti-aging no Kiso to sono Jicchi Chiryo eno Katsuyo no Jissai Tonyobyo to Anti-aging", MEDICAL PRACTICE, vol. 31, no. 7, 2014, pages 1111 - 1115, XP009518286, ISSN: 0910-1551
BONHEI TAKASE ET AL.: "Kandomyaku Shikkan o Gappei shita Tonyobyo Shorei ni Okeru SGLT2 Sogaiyaku no Kekkan Naihi Kino ni Oyobosu Eikyo; Preliminary Study", JOURNAL OF THE JAPANESE CORONARY ASSOCIATION, vol. 22, 24 November 2016 (2016-11-24), pages 196, XP009518639, ISSN: 1341-7703
SHIORI OGIWARA ET AL.: "Roka Sokushin Model Mouse Jinzo ni Okeru Toyusotai no Hen'i to No Kino Teika", ABSTRACTS OF 131ST ANNUAL MEETING OF PHARMACEUTICAL SOCIETY OF JAPAN 3, vol. 131, 2011, pages 160, XP009515161, ISSN: 0918-9823
MINAMINO, T. ET AL.: "A crucial role for adipose tissue p53 in the regulation of insulin resistance", NAT. MED., vol. 15, 2009, pages 1082 - 1087, XP055291725, DOI: doi:10.1038/nm.2014
DIMRI, G.P. ET AL., PROC. NATL. ACAD. SCI. U.S.A., vol. 92, no. 20, 1995, pages 9363 - 9367
See also references of EP 3508222A4
ATSUSHI OBATA ET AL.: "Tokushu 2-gata Tonyobyo no Atarashii Chiryo Senryaku: Shinki Tonyobyo Chiryoyaku o do Katsuyo suru? I.SGLT2 Sogaiyaku no Tonyobyo Chiryo ni Okeru Senryakuteki Ichizuke Tekishita Kanjazo", TEKISANAI KANJAZO, DIABETES, vol. 7, no. 6, 2015, pages 26 - 34, XP009518399, ISBN: 978-4-287-82072-8
IZUMI HIRATSUKA ET AL.: "Jicchi Ika no Tameno Kokarei Igaku no Rinsho Seminor Shinpo shita Anti-aging no Kiso to sono Jicchi Chiryo eno Katsuyo no Jissai Tonyobyo to Anti-aging", MEDICAL PRACTICE, vol. 31, no. 7, 2014, pages 1111 - 1115, XP009518286, ISSN: 0910-1551
BONHEI TAKASE ET AL.: "Kandomyaku Shikkan o Gappei shita Tonyobyo Shorei ni Okeru SGLT2 Sogaiyaku no Kekkan Naihi Kino ni Oyobosu Eikyo; Preliminary Study", JOURNAL OF THE JAPANESE CORONARY ASSOCIATION, vol. 22, 24 November 2016 (2016-11-24), pages 196, XP009518639, ISSN: 1341-7703
SHIORI OGIWARA ET AL.: "Roka Sokushin Model Mouse Jinzo ni Okeru Toyusotai no Hen'i to No Kino Teika", ABSTRACTS OF 131ST ANNUAL MEETING OF PHARMACEUTICAL SOCIETY OF JAPAN 3, vol. 131, 2011, pages 160, XP009515161, ISSN: 0918-9823
MINAMINO, T. ET AL.: "A crucial role for adipose tissue p53 in the regulation of insulin resistance", NAT. MED., vol. 15, 2009, pages 1082 - 1087, XP055291725, DOI: doi:10.1038/nm.2014
DIMRI, G.P. ET AL., PROC. NATL. ACAD. SCI. U.S.A., vol. 92, no. 20, 1995, pages 9363 - 9367
See also references of EP 3508222A4
Attorney, Agent or Firm:
TSUKUNI & ASSOCIATES et al. (JP)
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