Title:
DRUG FOR SIMULTANEOUSLY REDUCING RISK OF HAEMORRHAGE AND MICROVASCULAR OBSTRUCTION
Document Type and Number:
WIPO Patent Application WO/2019/237995
Kind Code:
A1
Abstract:
Provided in the present invention is a drug for simultaneously reducing the risk of haemorrhage and microvascular obstruction. Specifically, the present invention provides a composition, the composition comprising (a) a therapeutically effective dose of a first active ingredient, the first active ingredient being clopidogrel or a pharmaceutically acceptable salt thereof; (b) a therapeutically effective dose of a second active ingredient, the second active ingredient being salvianolic acid B or a pharmaceutically acceptable salt thereof; and (c) a therapeutically effective dose of a third active ingredient, the third active ingredient being ginsenoside Rg1 or a pharmaceutically acceptable salt thereof. The first active ingredient, the second active ingredient, and the third active ingredient of the present invention can produce a bilateral synergistic protective effect, effectively reducing microvascular obstruction and effectively preventing haemorrhage, and reducing the dosage of single drugs and reducing drug toxicity.
Inventors:
JIANG BAOHONG (CN)
WANG LINLIN (CN)
WANG LINLIN (CN)
Application Number:
PCT/CN2019/090431
Publication Date:
December 19, 2019
Filing Date:
June 06, 2019
Export Citation:
Assignee:
SHANGHAI INST MATERIA MEDICA CAS (CN)
International Classes:
A61K31/4365; A61K31/343; A61K31/704; A61P9/10; A61P9/14
Foreign References:
| CN101084998A | 2007-12-12 |
Other References:
ZHANG, LANLAN ET AL.: "Therapeutic effects of Hongjingtian Injection combined with Clopidogrel on Unstable Angina Pectoris", HEBEI MEDICAL PECTORIS, vol. 14, no. 38, 31 July 2016 (2016-07-31), pages 2140 - 2142
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
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