DRUGS FO RPROMOTING THE PROLIFERATION, DIFFERENTIATION AND/OR SURVIVAL OF GLIAL CELLS CONTAINING CYCLIC PHOSPHATIDIC ACID

Title:

DRUGS FO RPROMOTING THE PROLIFERATION, DIFFERENTIATION AND/OR SURVIVAL OF GLIAL CELLS CONTAINING CYCLIC PHOSPHATIDIC ACID

Document Type and Number:

WIPO Patent Application WO/2002/083149

Kind Code:

A1

Abstract:

It is intended to clarify a novel physiological activity of cPA on glial cells to thereby disclose its possibility as a remedy for brain nerve disorders such as Alzheimer's disease, ischemic nerve disorders and Parkinson's disease (in particular, cerebrovascular dementia such as Binswanger's dementia). Namely, remedies for cerebrovascular dementia which contain as the active ingredient a cyclic phosphatidic acid derivative having a cyclic phosphate structure at the glycerol sn-2- and 3-positions

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Inventors:

MUROFUSHI KIMIKO (JP)
ASOU HIROAKI (JP)
KOBAYASHI TETSUYUKI (JP)

Application Number:

PCT/JP2002/003659

Publication Date:

October 24, 2002

Filing Date:

April 12, 2002

Export Citation:

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Assignee:

GENCOM CORP (JP)
MUROFUSHI KIMIKO (JP)
ASOU HIROAKI (JP)
KOBAYASHI TETSUYUKI (JP)

International Classes:

C12N5/07; A61K31/661; A61P25/00; A61P25/28; A61P43/00; C12N5/079; (IPC1-7): A61K31/661; A61P25/00; A61P25/28; A61P43/00

Domestic Patent References:

WO2000057865A2	2000-10-05
WO1999047101A2	1999-09-23

Foreign References:

US6150345A	2000-11-21
JPH07149772A	1995-06-13

Other References: