Title:
DRUGS INDUCING ULTRASONIC ACTION AND APPARATUS WHEREIN THE DRUGS ARE USED
Document Type and Number:
WIPO Patent Application WO/1998/001131
Kind Code:
A1
Abstract:
Drugs containing compounds of xanthene dyes or derivatives thereof (including dimers) having xanthene ring(s) and inducing an ultrasonic action of lowering the threshold of acoustic strength causing acoustic cavitation, wherein any of R?1� to R?8� bonded to carbon atoms of the xanthene dye skeleton is a functional group capable of chemically binding to a halogeno, thiol or amino group (selected from among halogenated acetamide, maleimide, aziridine, isothiocyanate, succinimide and sulfonyl chloride). Because of being able to lower the threshold, these drugs make it possible to safely treat benign or malignant tumors or stones by the irradiation with ultrasonic waves of a low acoustic strenght.
Inventors:
KAWABATA KENICHI (JP)
UMEMURA SHINICHIRO (JP)
SASAKI KAZUAKI (JP)
SUGITA NAMI (JP)
UMEMURA SHINICHIRO (JP)
SASAKI KAZUAKI (JP)
SUGITA NAMI (JP)
Application Number:
PCT/JP1997/002285
Publication Date:
January 15, 1998
Filing Date:
July 02, 1997
Export Citation:
Assignee:
HITACHI LTD (JP)
KAWABATA KENICHI (JP)
UMEMURA SHINICHIRO (JP)
SASAKI KAZUAKI (JP)
SUGITA NAMI (JP)
KAWABATA KENICHI (JP)
UMEMURA SHINICHIRO (JP)
SASAKI KAZUAKI (JP)
SUGITA NAMI (JP)
International Classes:
A61K41/00; C07D311/82; A61B17/22; A61N7/00; (IPC1-7): A61K31/35; A61B17/36
Foreign References:
| JPH0629196B2 | 1994-04-20 | |||
| JPH08176017A | 1996-07-09 | |||
| JPS63264064A | 1988-10-31 |
Attorney, Agent or Firm:
Ogawa, Katsuo (5-1, Marunouchi 1-chom, Chiyoda-ku Tokyo 100, JP)
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