Title:
CDK8/19 DUAL INHIBITORS AND METHODS OF USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/241627
Kind Code:
A1
Abstract:
The disclosure provides for compounds and methods for modulating or inhibiting CDK8/19.
Inventors:
DING XIAO (CN)
REN FENG (CN)
XU JIANYU (CN)
LIU YINGTAO (CN)
WU JIANPING (CN)
LIU XIAOSONG (CN)
REN FENG (CN)
XU JIANYU (CN)
LIU YINGTAO (CN)
WU JIANPING (CN)
LIU XIAOSONG (CN)
Application Number:
PCT/CN2023/100207
Publication Date:
December 21, 2023
Filing Date:
June 14, 2023
Export Citation:
Assignee:
INSILICO MEDICINE IP LTD (CN)
International Classes:
C07D403/04; A61K31/4184; A61K31/4353; A61K31/496; A61P35/00; A61P35/02; A61P37/00; A61P37/02; C07D401/04; C07D401/14; C07D403/14; C07D471/16; C07D487/16
Foreign References:
| CN104903321A | 2015-09-09 | |||
| CN108348509A | 2018-07-31 | |||
| CN104936951A | 2015-09-23 | |||
| CN101568530A | 2009-10-28 |
Other References:
DATABASE Registry 17 November 2021 (2021-11-17), ANONYMOUS : " 4H-Imidazo[4,5,1-ij]quinoline, 7,8,9-tribromo-5,6-dihydro-2-(1- piperazinyl)- (CA INDEX NAME)", XP093119028, retrieved from STNext Database accession no. 1609453-35-1
DATABASE Registry 20 July 2014 (2014-07-20), ANONYMOUS : "1H-Benzimidazole, 5,6-dibromo-1-cyclopropyl-4-nitro-2-(1-piperazinyl)- (CA INDEX NAME)", XP093119022, retrieved from STNext Database accession no. 1616358-75-8
DATABASE Registry 20 July 2014 (2014-07-20), ANONYMOUS : "1H-Benzimidazole, 5,6-dibromo-1-cyclopropyl-4-nitro-2-(1-piperazinyl)- (CA INDEX NAME)", XP093119022, retrieved from STNext Database accession no. 1616358-75-8
Attorney, Agent or Firm:
AFD CHINA INTELLECTUAL PROPERTY LAW OFFICE (CN)
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