Title:
DYE FOR PATHOLOGICAL DIAGNOSIS, CELL NUCLEUS STAINING METHOD, METHOD FOR PRODUCING PATHOLOGICAL SPECIMEN, AND PIGMENT
Document Type and Number:
WIPO Patent Application WO/2018/155694
Kind Code:
A1
Abstract:
The present invention provides: a dye for pathological diagnosis comprising a pigment represented by a formula (1); a cell nucleus staining method and method for producing a pathological specimen using this dye; and a pigment that is preferable as the pigment component of the dye. R1 through R8 and R11 and R12 each represent a hydrogen atom or a substituent group. R13 through R15 each represent a hydrogen atom or a substituent group. A1 and A2 each represent -O-, -S-, -Se-, -NR16-, or -CR17R18-, and R16 through R18 each represent a hydrogen atom or a substituent group. n1 is an integer of 0 to 3, and m is an integer of 1 to 4. X- shows an anionic counterion.
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Inventors:
WATANABE KOUSUKE (JP)
SASAKI KOUITSU (JP)
MAKITA KEIKO (JP)
SASAKI KOUITSU (JP)
MAKITA KEIKO (JP)
Application Number:
PCT/JP2018/007050
Publication Date:
August 30, 2018
Filing Date:
February 26, 2018
Export Citation:
Assignee:
FUJIFILM CORP (JP)
International Classes:
C09B23/00; C09B67/20; C09B67/44; G01N33/48
Domestic Patent References:
| WO2014136776A1 | 2014-09-12 |
Foreign References:
| JP2015007118A | 2015-01-15 | |||
| JP2010148447A | 2010-07-08 | |||
| JPH02225476A | 1990-09-07 | |||
| JP2008533491A | 2008-08-21 | |||
| JP2012526862A | 2012-11-01 | |||
| JP2014174018A | 2014-09-22 | |||
| JP2002541219A | 2002-12-03 |
Other References:
JI, C. D. ET AL.: "An amphiphilic squarylium indocyanine dye for long-term tracking of lysosomes", JOURNAL OF MATERIALS CHEMISTRY B, MATERIALS FOR BIOLOGY AND MEDICINE, vol. 3, no. 38, 2015, pages 7494 - 7498, XP055537486
YAO, D. F. ET AL., ACS APPLIED MATERIALS & INTERFACES, vol. 8, no. 9, 2016, pages 5847 - 5856, XP055537490
KARPENKO, I. A. ET AL.: "Squaraine as a bright, stable and environment-sensitive far-red label for receptor-specific cellular imaging", CHEMICAL COMMUNICATIONS, vol. 51, 2015, pages 2960 - 2963, XP055537497
YAO, D. F. ET AL., ACS APPLIED MATERIALS & INTERFACES, vol. 8, no. 9, 2016, pages 5847 - 5856, XP055537490
KARPENKO, I. A. ET AL.: "Squaraine as a bright, stable and environment-sensitive far-red label for receptor-specific cellular imaging", CHEMICAL COMMUNICATIONS, vol. 51, 2015, pages 2960 - 2963, XP055537497
Attorney, Agent or Firm:
IIDA & PARTNERS et al. (JP)
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