EBOLA VIRUS-SPECIFIC MIRNA AND METHOD FOR INHIBITING EBOLA VIRUS BY MIRNA

Title:

EBOLA VIRUS-SPECIFIC MIRNA AND METHOD FOR INHIBITING EBOLA VIRUS BY MIRNA

Document Type and Number:

WIPO Patent Application WO/2016/034111

Kind Code:

A1

Abstract:

Provided are Ebola virus-specific microRNA precursor sequences or mature sequences thereof and a use thereof in the preparation of reagents and kits for detecting the Ebola virus. Also provided are inhibitors aimed at the microRNA precursor sequences or mature sequences thereof and a use thereof in treating Ebola virus infections.

Inventors:

ZHANG CHENYU (CN)
LIANG HONGWEI (CN)
ZHOU ZHEN (CN)
ZENG KE (CN)
CHEN XI (CN)

Application Number:

PCT/CN2015/088803

Publication Date:

March 10, 2016

Filing Date:

September 01, 2015

Export Citation:

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Assignee:

JIANGSU MICROMEDMARK BIOTECH CO LTD (CN)

International Classes:

A61K48/00; A61K36/185; A61K36/195; A61K36/31; A61K36/355; A61K36/48; A61K36/76; A61K36/81; A61P31/14; C12N15/113; C12Q1/70

Domestic Patent References:

WO2013066442A2

2013-05-10

Foreign References:

CN103589721A	2014-02-19
CN101285100A	2008-10-15

Other References:

YANG ZHEN ET AL.: "Research Progress of Viral MicroRNA", ACTABIOPHYSICA SINICA, vol. 23, no. 1, 28 February 2007 (2007-02-28), pages 1 - 10, ISSN: 1000-6737
YANG, ZHEN ET AL.: "Research Progress of Viral MicroRNA", ACTABIOPHYSICA SINICA, vol. 23, no. 1, 28 February 2007 (2007-02-28), pages 1 - 10, ISSN: 1000-6737
SPURGERS, K.B. ET AL.: "Toward RNA Interference-Based Therapy for Filovirus Infections", DRUG DEVELOPMENT RESEARCH, vol. 70, 31 December 2009 (2009-12-31), pages 246 - 254, XP002610584, ISSN: 0272-4391

Attorney, Agent or Firm:

XU & PARTNERS, LLC. (CN)
上海一平知识产权代理有限公司 (CN)

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