Title:
ENTERIC COATED ALIPHATIC AMINE POLYMER BILE ACID SEQUESTRANTS
Document Type and Number:
WIPO Patent Application WO2005065291
Kind Code:
A3
Abstract:
Tablets, capsules, sachets, or papers having one or more aliphatic amine polymers allow for the targeted release of the polymers at a specific region of the gastrointestinal tract, especially the small intestine. These tablets, capsules, sachets, or papers are useful in a method for lowering cholesterol in a mammal in need thereof. The tablet includes a tablet core having an aliphatic amine polymer, and an enteric coating for the core. The capsule, sachet or paper includes a plurality of beads where the beads have a bead core having an aliphatic amine polymer, an enteric coating therefor and optionally a water-soluble coating.
Inventors:
BHAGAT HITESH R (US)
DONOVAN JOANNE M (US)
BRAUNLIN WILLIAM (US)
SACCHIERO ROBERT (US)
DONOVAN JOANNE M (US)
BRAUNLIN WILLIAM (US)
SACCHIERO ROBERT (US)
Application Number:
PCT/US2004/043537
Publication Date:
February 09, 2006
Filing Date:
December 23, 2004
Export Citation:
Assignee:
GENZYME CORP (US)
BHAGAT HITESH R (US)
DONOVAN JOANNE M (US)
BRAUNLIN WILLIAM (US)
SACCHIERO ROBERT (US)
BHAGAT HITESH R (US)
DONOVAN JOANNE M (US)
BRAUNLIN WILLIAM (US)
SACCHIERO ROBERT (US)
International Classes:
A61K9/22; A61K9/28; A61K9/50; A61K31/785
Domestic Patent References:
| WO1994028881A1 | 1994-12-22 | |||
| WO1993000915A1 | 1993-01-21 | |||
| WO2001060392A1 | 2001-08-23 | |||
| WO2001028527A2 | 2001-04-26 |
Foreign References:
| EP0922461A1 | 1999-06-16 | |||
| EP0637447A2 | 1995-02-08 | |||
| EP1273307A1 | 2003-01-08 |
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