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Title:
EQUIPMENT AND METHOD FOR FEEDING LIQUID GRADIENT IN NANO/MICRO LIQUID CHROMATOGRAPHY
Document Type and Number:
WIPO Patent Application WO/2004/010134
Kind Code:
A1
Abstract:
Equipment and a method for feeding liquid gradient in a nano/micro liquid chromatography capable of improving a liquid feeding performance at the time of mixing of solvent, the equipment and method as the first embodiment of this invention wherein an open/close means (160) capable opening and closing a second solvent flow passage (150) is installed near the solvent mixing part (152) of a liquid feeding system (130), a flow passage ranging from a metering pump (146) at a liquid feeding part (142) to the open/close means (160) is filled with second solvent beforehand, and a proper pressure is added to the solvent so as to suppress the inflow of initial solvent into the second solvent flow passages; the equipment and method as the second embodiment of this invention wherein the liquid with a small compressibility is filled in the flow passage ranging from the metering pump at the liquid feeding part to a part of the subsequent solvent flow passage beforehand the second solvent is filled therein by a necessary amount continuously with the liquid so as to suppress the inflow of the initial solvent into the second solvent flow passage, whereby the liquid feeding performance can be increased.

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Inventors:
KUDO KENICHI (JP)
YAMAUCHI YOSHIO (JP)
Application Number:
PCT/JP2003/009375
Publication Date:
January 29, 2004
Filing Date:
July 24, 2003
Export Citation:
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Assignee:
KYA TECHNOLOGIES CORP (JP)
KUDO KENICHI (JP)
YAMAUCHI YOSHIO (JP)
International Classes:
G01N30/26; G01N30/32; G01N30/34; G01N30/36; G01N30/60; (IPC1-7): G01N30/34
Foreign References:
JPS5278498A1977-07-01
JPS5071389A1975-06-13
JPS5344085A1978-04-20
JPH11502931A1999-03-09
Other References:
See also references of EP 1524520A4
Attorney, Agent or Firm:
Iwahashi, Yuji (Higashikanagawa Kanagawa-k, Yokohama-shi Kanagawa, JP)
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