Title:
ESTROGEN BETA RECEPTOR AGONISTS TO PREVENT OR REDUCE THE SEVERITY OF CARDIOVASCULAR DISEASE
Document Type and Number:
WIPO Patent Application WO2004047726
Kind Code:
A3
Abstract:
A method for preventing or treating vascular hyperreactivity in which a chemical compound that is an estrogen beta receptor agonist is administered to a subject suffering from or at risk of vascular hyperreactivity. Preferably, the administration is topically to the skin.
Inventors:
HERMSMEYER R KENT (US)
Application Number:
PCT/US2003/034120
Publication Date:
September 16, 2004
Filing Date:
October 27, 2003
Export Citation:
Assignee:
DIMERA INC (US)
HERMSMEYER R KENT (US)
HERMSMEYER R KENT (US)
International Classes:
A61K31/57; (IPC1-7): A61K31/56
Foreign References:
| US2584271A | 1952-02-05 |
Other References:
THOMPSON ET AL: "Long-term Estradiol Replacement Decreases Contractility of Guinea Pig Coronary Arteries to the Thromboxane Mimetic U46619", CIRCULATION, vol. 95, no. 3, 1997, pages 709 - 714, XP002980325
SETCHELL ET AL: "Isoflavone content of infant formulas and the metabolic fate of these phytoestrogens in early life", AM. J. CLIN. NUTR., vol. 68, 1998, pages 1453S - 1461S, XP002980326
SETCHELL ET AL: "Isoflavone content of infant formulas and the metabolic fate of these phytoestrogens in early life", AM. J. CLIN. NUTR., vol. 68, 1998, pages 1453S - 1461S, XP002980326
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