Title:
ETOMIDATE DERIVATIVE AND INTERMEDIATE, PREPARATION METHOD AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/059827
Kind Code:
A1
Abstract:
Disclosed are an etomidate derivative of formula 1 or a pharmaceutically acceptable salt, a polymorph or a solvate thereof, a pharmaceutical composition and a kit comprising the etomidate derivative, and an intermediate, a preparation method and a use of the etomidate derivative. The etomidate derivative not only has a good anaesthetic activity, rapid onset time and short acting time, but also has no inhibitory effect on the secretion of corticosteroids in animals, and thus has both a good anaesthetic effect and good safety.
Inventors:
LI QINGENG (CN)
WANG TAO (CN)
ZENG LINGGUO (CN)
ZHANG GUISHENG (CN)
XU XIANGQING (CN)
REN LIANG (CN)
WANG TAO (CN)
ZENG LINGGUO (CN)
ZHANG GUISHENG (CN)
XU XIANGQING (CN)
REN LIANG (CN)
Application Number:
PCT/CN2016/101696
Publication Date:
April 13, 2017
Filing Date:
October 10, 2016
Export Citation:
Assignee:
JIANGSU NHWALUOKANG PHARMCEUTICAL RES AND DEV CO LTD (CN)
International Classes:
C07D233/90; A61P23/00
Foreign References:
| CN103739553A | 2014-04-23 | |||
| CN104706587A | 2015-06-17 |
Other References:
See also references of EP 3360863A4
Attorney, Agent or Firm:
NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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