Title:
EVALUATION MARKER REFLECTING EFFICACY OF CANCER TREATMENT COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2022/075318
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing: a method of detecting an evaluation marker that reflects the efficacy of a cancer treatment composition on pancreatic tumor; a cancer treatment composition; a method of using the evaluation marker; the evaluation marker; a test reagent; and an evaluation device that reflects the efficacy of a cancer treatment composition. This problem is solved by a method of detecting an evaluation marker that reflects the efficacy of a cancer treatment composition on a pancreatic tumor patient with peritoneal dissemination, said method comprising a step for detecting CXCL12 in an area of interest including pancreatic tumor cells in a tissue that is collected from the target patient, wherein the cancer treatment composition comprises a paclitaxel compound.
Inventors:
SATOI SOHEI (JP)
YAMAMOTO TOMOHISA (JP)
RYOTA HIRONORI (JP)
YAMAKI SO (JP)
ISHIDA MITSUAKI (JP)
YAMAMOTO TOMOHISA (JP)
RYOTA HIRONORI (JP)
YAMAKI SO (JP)
ISHIDA MITSUAKI (JP)
Application Number:
PCT/JP2021/036820
Publication Date:
April 14, 2022
Filing Date:
October 05, 2021
Export Citation:
Assignee:
KANSAI MEDICAL UNIV EDUCATIONAL CORPORATION (JP)
International Classes:
A61P35/00; A61K31/337; G01N33/53; G01N33/574
Domestic Patent References:
| WO2016068160A1 | 2016-05-06 |
Foreign References:
| JP2006522148A | 2006-09-28 | |||
| CN105137078A | 2015-12-09 |
Other References:
YAMADA S, FUJII T, YAMAMOTO T, TAKAMI H, YOSHIOKA I, YAMAKI S, SONOHARA F, SHIBUYA K, MOTOI F, HIRANO S, MURAKAMI Y, INOUE H, HAYA: "Phase I/II study of adding intraperitoneal paclitaxel in patients with pancreatic cancer and peritoneal metastasis", BRITISH JOURNAL OF SURGERY, vol. 107, no. 13, 12 November 2020 (2020-11-12), GB , pages 1811 - 1817, XP055920164, ISSN: 0007-1323, DOI: 10.1002/bjs.11792
ISOHEI SATO: "Diagnosis and Treatment of Peritoneal Metastasis of Pancreatic Cancer", JAPAN JOURNAL OF CANCER CLINICS, vol. 64, no. 2, 1 January 2018 (2018-01-01), JP , pages 97 - 102, XP009535675, ISSN: 0021-4949
ISOHEI SATO: "Diagnosis and Treatment of Peritoneal Metastasis of Pancreatic Cancer", JAPAN JOURNAL OF CANCER CLINICS, vol. 64, no. 2, 1 January 2018 (2018-01-01), JP , pages 97 - 102, XP009535675, ISSN: 0021-4949
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
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