EXTERNAL PREPARATIONS FOR PERCUTANEOUS ABSORPTION

Title:

EXTERNAL PREPARATIONS FOR PERCUTANEOUS ABSORPTION

Document Type and Number:

WIPO Patent Application WO/1998/031369

Kind Code:

A1

Abstract:

External preparations of methotrexate for percutaneous absorption, having systemic therapeutic effects on, for example, chronic inflammatory diseases such as autoimmune diseases (rheumatoid arthritis, etc.) and cancerous diseases such as leukemia and aiming at relieving the side effects of methotrexate and improving the compliance and quality of life of patients. These preparations contain a chemical (i.e., methotrexate) in the bases and exert systemic therapeutic effects on the patients.

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Inventors:

ITO KAZUSHI (JP)
KAWAMORI TADAO (JP)
MATSUDA MASANORI (JP)
KURIYAMA KIYOSHI (JP)

Application Number:

PCT/JP1998/000123

Publication Date:

July 23, 1998

Filing Date:

January 16, 1998

Export Citation:

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Assignee:

SEKISUI CHEMICAL CO LTD (JP)
ITO KAZUSHI (JP)
KAWAMORI TADAO (JP)
MATSUDA MASANORI (JP)
KURIYAMA KIYOSHI (JP)

International Classes:

A61K9/06; A61K9/70; A61K31/519; (IPC1-7): A61K31/505; A61K9/06; A61K9/70; A61K47/02; A61K47/06

Domestic Patent References:

WO1998003641A1

1998-01-29

Foreign References:

JPS6327432A

1988-02-05

Attorney, Agent or Firm:

Yasutomi, Yasuo (4F 14-22, Nishinakajima 5-chome, Yodogawa-k, Osaka-shi Osaka 532, JP)

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