Title:
EXTRACELLULAR VESICLE COMPRISING ANTIGENIC PROTEIN OR GENE ENCODING SAME PROTEIN, AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/014894
Kind Code:
A1
Abstract:
The present invention relates to an extracellular vesicle comprising an antigenic protein or a gene encoding the antigenic protein and uses thereof and, more specifically, to an extracellular vesicle comprising an antigenic protein derived from viruses, microorganisms, or cancer cells, or to a gene encoding the antigenic protein, or to a vaccine composition for the prevention or treatment of viral infections, microbial infections, or cancer comprising same. The extracellular vesicle, or the vaccine composition comprising same, according to the present invention, is expected to be useful in the development of vaccines for the prevention or treatment of various diseases, including viral infections, microbial infections, or cancer, as a platform applicable to various diseases with excellent antigen-specific immune response inducing effects and stability.
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Inventors:
KWON KI HWAN (KR)
CHUNG JI HWA (KR)
KIM KYOUNG HWA (KR)
CHUNG JI HWA (KR)
KIM KYOUNG HWA (KR)
Application Number:
PCT/KR2023/010004
Publication Date:
January 18, 2024
Filing Date:
July 13, 2023
Export Citation:
Assignee:
UNIV EWHA IND COLLABORATION (KR)
EXOLLENCE CO LTD (KR)
EXOLLENCE CO LTD (KR)
International Classes:
C12N15/88; A23L33/13; A61K39/00; A61K39/12; A61P31/12; A61P35/00; C07K14/005; C07K14/47
Domestic Patent References:
| WO2022066898A2 | 2022-03-31 |
Foreign References:
| KR20220004035A | 2022-01-11 | |||
| US20190112351A1 | 2019-04-18 |
Other References:
LIU HAN, GENG ZHEN, SU JIACAN: "Engineered mammalian and bacterial extracellular vesicles as promising nanocarriers for targeted therapy", EXTRACELLULAR VESICLES AND CIRCULATING NUCLEIC ACIDS, vol. 3, no. 1, pages 63 - 86, XP093128538, ISSN: 2767-6641, DOI: 10.20517/evcna.2022.04
NEMATI MOHADESEH, SINGH BIPIN, MIR RAKEEB AHMAD, NEMATI MAHDIEH, BABAEI AZADEH, AHMADI MAHDI, RASMI YOUSEF, GOLEZANI AFSANEH GHOLI: "Plant-derived extracellular vesicles: a novel nanomedicine approach with advantages and challenges", CELL COMMUNICATION AND SIGNALING, vol. 20, no. 1, 23 May 2022 (2022-05-23), XP093038600, DOI: 10.1186/s12964-022-00889-1
NEMATI MOHADESEH, SINGH BIPIN, MIR RAKEEB AHMAD, NEMATI MAHDIEH, BABAEI AZADEH, AHMADI MAHDI, RASMI YOUSEF, GOLEZANI AFSANEH GHOLI: "Plant-derived extracellular vesicles: a novel nanomedicine approach with advantages and challenges", CELL COMMUNICATION AND SIGNALING, vol. 20, no. 1, 23 May 2022 (2022-05-23), XP093038600, DOI: 10.1186/s12964-022-00889-1
Attorney, Agent or Firm:
THEWAVE IP LAW FIRM (KR)
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