Title:
FEEDER CELLS, CELL SHEET, PRODUCTION METHOD FOR FEEDER CELLS AND CELL SHEET, AND METHOD FOR MAINTAINING OR PROLIFERATING CELLS USING FEEDER CELL
Document Type and Number:
WIPO Patent Application WO/2024/053684
Kind Code:
A1
Abstract:
[Problem] To provide feeder cells for bidimensional culturing for maintenance or proliferation of cells and a method for producing feeder cells, the feeder cells being for cells for which maintenance and proliferation by bidimensional culturing is considered difficult. [Solution] In the present invention, feeder cells are prepared by proliferating and isolating fibroblast-like cells derived from a bowel structure that is produced from pluripotent stem cells and that includes endoderm-derived cells and mesoderm-derived cells.
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Inventors:
MORINAGA KENICHI (JP)
UMEZAWA AKIHIRO (JP)
UMEZAWA AKIHIRO (JP)
Application Number:
PCT/JP2023/032577
Publication Date:
March 14, 2024
Filing Date:
September 06, 2023
Export Citation:
Assignee:
DAINIPPON PRINTING CO LTD (JP)
NAT CT CHILD HEALTH & DEV (JP)
NAT CT CHILD HEALTH & DEV (JP)
International Classes:
C12N5/071
Domestic Patent References:
| WO2018230102A1 | 2018-12-20 |
Foreign References:
| JP2022007610A | 2022-01-13 |
Other References:
HAJIME UCHIDA, MACHIDA MASAKAZU, MIURA TAKUMI, KAWASAKI TOMOYUKI, OKAZAKI TAKUYA, SASAKI KENGO, SAKAMOTO SEISUKE, OHUCHI NORIAKI, : "A xenogeneic-free system generating functional human gut organoids from pluripotent stem cells", JCI INSIGHT, vol. 2, no. 1, 1 January 2017 (2017-01-01), pages 1 - 13, XP055645928, DOI: 10.1172/jci.insight.86492
YOKOMIZO R, FUJIKI Y, KISHI H, SAGO H, OKAMOTO A: "P-801 - Endometrial regeneration with establishment of improved culture methods for endometrial epithelial cells: co-culture with feeder cells", ABSTRACTS OF THE 36TH ANNUAL MEETING OF THE ESHRE, 1 July 2020 (2020-07-01), pages i501, XP093148353, Retrieved from the Internet
YOKOMIZO R, FUJIKI Y, KISHI H, SAGO H, OKAMOTO A: "P-801 - Endometrial regeneration with establishment of improved culture methods for endometrial epithelial cells: co-culture with feeder cells", ABSTRACTS OF THE 36TH ANNUAL MEETING OF THE ESHRE, 1 July 2020 (2020-07-01), pages i501, XP093148353, Retrieved from the Internet
Attorney, Agent or Firm:
MIYAJIMA Manabu et al. (JP)
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