DESCRIPTION

TECHNICAL FIELD OF THE INVENTION

[0001 ]The present invention refers to an apparatus for feeding pharmaceutical products and to a component of the same, such as a vibro-feeder container for pharmaceutical products.

[0002] In particular, the present invention refers to a feeding apparatus and to a vibro-feeder container that are configured to receive a plurality of pharmaceutical products charged in a random state and, subsequently, to feed the latter in an automatic manner with a specific arrangement, preferably singularized.

PRIOR ART

[0003] Modern systems for management or processing pharmaceutical products, such as for example pharmaceutical compounds or compositions in the form of pills, tablets, capsules of the like, require a high degree of processing reliability conceived to achieve a desired arrangement, such as for example a singularization and to guarantee at the same time an efficient processing.

[0004] In particular, the steps of processes for managing or processing the pharmaceutical products require that a plurality of the latter are first received in a random state, or in bulk, and are subsequently fed in a specific arrangement for additional processes and/or equipment.

[0005] For example, during the steps of production, from a plant is collected inside a container a plurality of a pharmaceutical product of the same kind in a random state, for example pills of one kind of medicine produced by said plant. In the production plant, said pills are subsequently fed singularized to verification or testing steps, by means of suitable equipment to determine the conformity of the production-batch with given quality requirements.

[0006]Alternatively, packaging steps in an appropriate plant provide for a plurality of a given pharmaceutical product, for example pills of a given medicine, to be received from previous steps in a random state inside a container, for example from production-steps. In the plant, said pills are packaged by means of appropriate equipment according to a given arrangement, for example singularized inside respective blisters of a packaging support. [0007]Alternatively, health facilities, such as for example hospitals, receive from a manufacturer a plurality of pills of a given medicine in a random state inside a container. In the health facility, said pills are packaged by appropriate machines according to a given arrangement, for example singularized inside respective blisters of a packaging support or inside another type of packaging, for the subsequent steps of dispensing and administering them to patients.

[0008] However, in particular for pharmaceutical products, the different steps of management and processing must be carried out so as to prevent or reduce any contamination and/or alteration with foreign agents, such as organic or inorganic substances, dust, moisture, light and the like. In particular, steps of management and processing that require handling by a user, for example an employee or health operator, increase the probability of contaminating and/or altering the pharmaceutical products.

[0009]Specifically, it is desirable that the apparatuses and their components guarantee a high degree of reliability in the performance of the steps of the procedures adapted to obtain a desired arrangement with a high processing efficiency and, furthermore, that they prevent or reduce the probability of the pharmaceutical products being contaminated and/or altered. [0010]Consequently, there is the necessity of devising a solution that can meet the requirements described above.

SUMMARY OF THE INVENTION

[0011] An objective of the present invention is to provide a feeding apparatus for pharmaceutical products that is configured to receive the products in a random state and subsequently feed them in a given arrangement, preferably singularized, preventing or reducing the possibility of their being contaminated and/or altered.

[0012] In the scope of the above objective, one purpose of the present invention regards a feeding apparatus configured to reliably process a plurality of pharmaceutical products received in a random state, or in bulk.

[0013] A further purpose concerns a feeding apparatus that reliably guarantees the feeding of pharmaceutical products according to a given arrangement.

[0014] A further objective concerns a feeding apparatus configured to prevent or reduce any contamination and/or alteration of the pharmaceutical products with foreign agents, such as organic or inorganic substances, dust, moisture, light or the like.

[0015] A further objective regards a feeding apparatus configured to reduce the number of steps that require the handling of the product by a user.

[0016] A further objective regards a feeding apparatus that provides for a construction that is easy to design and produce on the basis of a management or processing system to which it is associated.

[0017] A further objective regards a feeding apparatus configured to guarantee a simple and intuitive use of the same.

[0018] A further objective regards a vibro-feeder container, for said feeding apparatus, that is configured to contain a plurality of pharmaceutical products in a random state, and that prevents or reduces any contamination and/or alteration of the same during processing with said feeding apparatus on in steps that precede said processing, for example during previous storage or transportation steps.

[0019] A further objective concerns a vibro-feeder container configured to guarantee a reliable processing of the plurality of pharmaceutical products by means of said feeding apparatus.

[0020]A further objective concerns a vibro-feeder container configured to guarantee a simple and intuitive use of the same in association with said feeding apparatus.

[0021 ]The above objective and purposes, and others that will become more evident in the following description, are achieved by means of a feeding apparatus, as defined in independent claim 1 , and a vibro-feeder container, as defined in the independent claim 11 . The preferred embodiments are defined in the dependent claims.

BRIEF DFESCRIPTION OF THE FIGURES

[0022]The further characteristics and advantages of the feeding apparatus and of the vibro-feeder container, according to the present invention, will become more evident in the following description relative to an embodiment given purely by way of non-limiting example, with reference to the following figures, wherein:

- Fig. 1 is a perspective view of a feeding apparatus for pharmaceutical products, according to a preferred embodiment of the invention, in a step of operation;

- Fig. 2 is a perspective view of the feeding apparatus of Fig. 1 in a further step of operation;

- Fig. 3 is a perspective view of the feeding apparatus of Figs. 1 and 2 in a still further step of operation;

- Fig. 4 is an enlarged perspective view of a portion of the feeding apparatus of Fig. 3;

- Fig. 5 is a perspective view of a part of a vibro-feeder system, opening means, and a pickup section of the feeding apparatus of Fig. 2;

- Fig. 6 is a perspective view of a vibration unit and of a vibro-feeder container, separated from each other, of a vibro-feeder system of the feeding apparatus of Figures 1 to 3;

- Fig. 7 is a perspective view of the vibro-feeder container of the vibro-feeder system of Fig. 6;

- Fig. 8 is a side view of the vibro-feeder container of Fig 7;

- Fig. 9 is a perspective view of a bowl element of the vibro-feeder container of

Fig. 7;

- Fig. 10 is a perspective view of a closure element of the vibro-feeder container of Fig. 7;

- Fig. 11 is a view from below of a horizontal section of the closure element of Fig. 10;

- Fig. 12 is a perspective view of the vibration unit of the vibro-feeder system of Fig. 6;

- Fig. 13 is a perspective view of the opening means of the feeding apparatus of Figs. 1 to 3;

- Fig. 14 is a perspective view of a pickup section of the feeding apparatus of Figs. 1 to 3;

- Fig. 15 is a perspective view of a pickup unit of pickup means of the feeding apparatus of Figs. 1 to 3;

- Fig 16 is a perspective view of a feeding apparatus for pharmaceutical products, according to a further embodiment of the present invention.

DETAILED DESCRIPTION OF THE INVENTION [0023] In the present description, the term “pharmaceutical product” is intended as being any pharmaceutical dosage form adapted for administering any pharmaceutical compound or composition, such as for example a pill, a compress, a pad, a suppository, or the like. Preferably, the pharmaceutical product is in the “uncovered” state, that is, a compress, a pad, a suppository in solid form made up of only the pharmaceutical compound or composition, without a containing packaging or shell. However, this selection is not limitative, and the pharmaceutical product can be any pharmaceutical dosage form, such as for example a capsule comprising a covering of edible material containing said pharmaceutical compound or composition, for example in powder, liquid or other similar form.

[0024]With reference to Figs. 1 to 15, a feeding apparatus 10 and its components will be described below according to a preferred embodiment of the present invention.

[0025]With particular reference to Figs. 1 to 4, the feeding apparatus 10 comprises preferably a vibro-feeder system 100, opening means 200, a pickup section 300, and pickup means 400. Moreover, the feeding apparatus 10 is preferably provided with an electronic command and control system (not shown in the figures) that is configured to coordinate the working of the various components, as is better explained below. In the most preferred embodiment, the feeding apparatus 10 also includes a framework (not shown in the figures) that supports the components on a support plane and possibly contains them in a box-like structure (not shown in the figures) that allows the access and/or inspection of one or more of the components (for example, the access to the vibro-feeder system 100).

[0026]The vibro-feeder system 100, with particular reference to Fig. 6, comprises a vibration unit 112 connected to a vibro-feeder container 110 preferably through releasable fastening means 114.

[0027]With reference to Figs. 6 to 11 , the vibro-feeder container 110 comprises in turn a bowl element 116 and a closure element 118.

[0028]The bowl element 116, with reference in particular to Fig. 9, comprises one or more walls 120 and a bottom 122 that define a cavity 124 adapted to receive a plurality of pharmaceutical products. Moreover, the cavity 124 is in outside communication with said bowl element 116 through an opening 126.

[0029] In the present embodiment, the bowl element 116 has substantially the structure of a truncated-cone shaped container in which the side wall defines said wall 120, the smaller base defines the bottom 122, and the larger base mainly defines the opening 126 that puts the cavity 124 in communication with the environment outside the bowl 116. Preferably, the bottom 122 has a convex shape so as to facilitate the movement of the pharmaceutical products toward a path 128, as will be better explained later.

[0030] In particular, in the most preferred embodiment, the opening 126 comprises a first opening portion 126a and a second opening portion 126b continuous to each other, i.e. connected to each other without interruption. The first opening portion 126a, having a greater extension than the second opening portion 126b, is arranged substantially at the larger base of the truncated-cone shaped container that defines the bowl element 116, while the second opening portion 126b is formed on an edge portion of the wall 120, and is preferably sized so as to allow the passage through it of at least one pharmaceutical product. [0031] However, this construction is not limitative and the bowl element 116 may provide other structures. For example, the bowl element 116 can be a cylindrical hollow element provided with an opening arranged only at one of its bases, as will be better explained later.

[0032] Moreover, the bowl element 116 comprises, within the cavity 124, a path 128 that preferably originates at the bottom 122. In particular, the path 128 extends preferably at least partially away from the bottom 122, along substantially the internal periphery of the wall 120 toward said opening 126, i.e. toward the second opening portion 126b, reaching a collecting region CR.

[0033] In the present embodiment, the path 128 defines substantially a helical ramp having an increasing radius starting from the bottom 122. However, this construction is not limitative and the path 128 may include other constructions. In particular, the shape and dimensions of the path 128 can be widely selected in the design phase of the bowl element 116, on the basis of the characteristics of shape and size of the pharmaceutical products and of the bowl element 116. [0034] In the present embodiment, the path 128, preferably originating from the bottom 122, ends at the second opening portion 126b of the opening 126 so as to allow the transportation of the pharmaceutical products from the bottom 122 toward the collecting region CR through the second opening portion 126b, by means of a vibrational movement generated by the vibration unit 112, as will be better explained below. In other words, the path 128 is configured to carry the pharmaceutical products, preferably one after the other to obtain a singularization, from the bottom 122 toward the collecting region CR through the second opening portion 126b.

[0035] Referring again to Figs. 6 to 11 , the closure element 118 is adapted to engage the opening 126 by reversibly closing the cavity124 with respect to the outside of said container of the vibro-feeder 110. In particular, the closure element 118 is configured to be at least partially displaced from the position of engaging the opening 126, so as to make said cavity 124 accessible from outside, for example through the second opening portion 126b, the first opening portion 126a, or both.

[0036] In the present embodiment, the closure element 118 is adapted to engage the first opening portion 126a and the second opening portion 126b of the opening 126 by reversibly closing the cavity 124. Preferably, the closure element 118 is also adapted to tightly close the cavity 124, for example by means of a sealing element (not shown in the figures) that engages the edge that defines the opening 126.

[0037] Preferably, the materials with which the bowl element 116 and the closure element 118 are made (in particular at the surfaces that define the cavity 124) are chosen from a group comprising materials, polymeric or metallic, that are in compliance with directives for the contact with pharmaceutical products, so as to prevent any contamination and/or alteration of the latter. Moreover, the surfaces of the bowl element 116 that define the cavity 124 and the path 128 preferably require a friction coefficient and/or a surface roughness appropriately selected to prevent damaging the pharmaceutical products due to the vibration of the vibro- feeder container 110, avoiding the formation of fine powder.

[0038] Preferably, with reference to Figs. 7 to 11 , the vibro-feeder container 110 also includes releasable locking means 130 configured to move between a locking position in which the closure element 118 is prevented from moving from the position of engaging the opening 126 (that is, the opening of the vibro-feeder container 110 is prevented), and a release position in which the displacement of the closure element 118 is allowed (that is, the opening of the vibro-feeder container 110 is allowed).

[0039] In the present embodiment, with particular reference to Figs. 9 and 11 , the releasable locking means 130 include recesses 132, lever elements 134, and pressing elements 136. The recesses 132 are formed on the external periphery of the wall 120 of the bowl element 116 substantially near the edge defining the opening 126 (one recess is visible in Fig. 9). While the lever elements 134 and the pressing elements 136 are arranged substantially at the edge regions of the closure element 118 (better visible in Fig. 11 ). The lever elements 134, having an elongate shape, are centrally pivoted on the closure element 118 and include a head portion 134a and a pressing portion 134b opposite to each other with respect to a fulcrum zone 134c on which they can rotate.

[0040] In particular, the pressing elements 136, such as elastic elements, are configured to act on a respective lever element 134 so that, when the closure element 118 engages the opening 126 of the bowl element 116 and closes the cavity 124, the head portion 134a of the lever elements 134 is urged to engage the respective recess 132, thus obtaining the locking position of the releasable locking means 130. From said locking position, it is possible to obtain the release position of the releasable locking means 130 by applying and preferably maintaining a pressure at the pressure portion 134b so as to overcome the force exerted by the respective pressing element 136.

[0041] In a most preferred embodiment, the releasable locking means 130 are substantially arranged internally to the body defining the closure element 118, and also include an access duct 137 configured to allow access to the pressure portion 134b from outside. In this state, it is possible to configure and properly dimension the access duct 137 so as not to make the pressure portion 134d manually accessible to a user, and so that it is instead accessible with unlocking means 212 of the opening means 200, as will be better explained below. Thus, with this most preferred embodiment, is prevented an accidental opening of the vibro-feeder container 110 by a user.

[0042] FI owe ver, it appears clear that the releasable locking means 130 may provide for other constructions. For example, it is possible to provide an embodiment in which the lever elements 134, arranged on the closure element 118, are replaced with cursor elements urged, by respective pressing elements, to releasably engage seats formed on the bowl element 116.

[0043]With reference in particular to Figs. 6 to 8, the vibro-feeder container 110, or its bowl element 116, also comprises a first connection portion 138 configured to cooperate with a second connection portion 140 of the vibration unit 112, so as to form said releasable fastening means 114 adapted to fix the vibro-feeder container 110 to the vibration unit 112, as will be better explained later.

[0044] In the present embodiment, the first connection portion 138 of the vibro- feeder container 110 is formed by a substantially cylindrical pin that projects, preferably from the bottom 122, externally to the bowl element 116, i.e. in a direction opposite to the cavity 124. The pin 138 is laterally provided with a groove 142. However, this selection is not limitative and the first connection portion can provide for other constructions or arrangements on the bowl element 116, for example it can project from the wall 120 of the bowl element 116.

[0045] Moreover, referring in particular to Figs. 6 and 12, in the present embodiment the second connection portion 140 of the vibration unit 112 is formed by a mandrel element configured to fasten itself in a releasable manner to the pin 138 by interference with the groove 142, forming therefore said releasable fastening means 114. Advantageously, in this state, the releasable fastening means 114 provide an effective construction and, at the same time, one that is simple and intuitive to use by a user who must substantially only place the vibro- feeder container 110 on the vibration unit 112.

[0046] In particular, in operative conditions, the vibration unit 112 is connected to the vibro-feeder container 110 to apply a vibratory movement to the latter, i.e. to its bowl element 116, so as to induce a movement of the pharmaceutical products from the bottom 122 toward the collecting region CR through the path 128. [0047] For this purpose, the vibration unit 112 comprises a conventional vibration actuating system 144, such as for example an electromagnet adapted to generate the vibratory movement, and said second connection portion 140. [0048]The vibration actuating system 144 is connected to the second connection portion 140 to transmit to the latter the vibratory movement generated. As mentioned previously, the second connection portion 140 of the vibration unit 112 is configured to cooperate in a releasable manner with the first connection portion 138 of the bowl element 116 of the vibro-feeder container 110, forming said releasable fastening means 114. In particular, the releasable fastening means 114 are adapted to transmit the vibratory movement generated by the vibration actuating system 144 to the bowl element 116 of the vibro-feeder container 110. Preferably, the bowl element 116, the first connection portion 138, and the second connection portion 140 are configured to vibrate as a single body, when fastened to each other.

[0049] In a most preferred embodiment, the releasable fastening means 114 are quick coupling means. Specifically, in the present invention the term “quick coupling means” refers to a connection requiring simple handling or instruments from a user so as to require short connecting times to facilitate the assembly/disassembly of the components, which in this case is the assembly/disassembly of the vibro-feeder container 110 on the vibration unit 112. For example, in the present embodiment, the mandrel element 140 is configured to automatically hold the first connection portion 138 with an elastic clamp at the moment when they are inserted one into the other. Subsequently, the first connection portion 138 is freed by the activation of a compressed-air system adapted to spread apart said elastic clamp of the mandrel element 140. Advantageously, in this state, the releasable fastening means 114 provide an effective construction and, at the same time, an additionally simple and intuitive handling by a user. However, this solution is not limitative, and further types of quick coupling means can be provided.

[0050] Moreover, the releasable fastening means 114 are preferably configured to allow the installation of the vibro-feeder container 110 on the vibration unit 112 with an established orientation with respect to the opening means 200, to the pickup section 300, and to the pickup means 400.

[0051] Referring to Figs. 6 to 8, the vibro-feeder container 110 includes preferably identification means 146 preferably arranged externally on the wall 120 of the bowl element 116. The identification means 146, such as for example a bar code, a QR code, a radio frequency identification system (RFID), a magnetic identification system, or the like, are adapted to provide information relative preferably to (or are adapted to identify) the vibro-feeder container 110 and/or the pharmaceutical products contained in it. For example, the identification means 126 can provide information relative to the type of pharmaceutical product, the batch of product, the date of production, and the like.

[0052] Moreover, with reference to Figs. 7, 10 and 11 , the closure element 118 of the vibro-feeder container 110 preferably includes a window portion 148. The window portion 148, such as a portion of the closure element 118 formed with transparent material, allows the inspection of the cavity 124 and the pharmaceutical products contained therein.

[0053] Moreover, with reference to Figs. 6 and 12, the vibration unit 112 preferably includes container sensors 150 configured to verify the presence of the vibro-feeder container 110 and/or its correct installation on the vibration unit 112 to ensure a given orientation with respect to the opening means 200, to the pickup section 300, and to the pickup means 400.

[0054]With reference to Figs. 1 to 4 and 13, the opening means 200 are configured to, preferably automatically, engage and displace in a reversible manner at least partially the closure element 118 from the position of engagement of the opening 126 of the bowl element 116, thus opening the vibro-feeder container 110. In this state, the opening means 200 make said cavity 124 of the bowl element 116, i.e. of the vibro-feeder container 110, accessible from outside (and vice versa) through at least one portion of said opening 126, for example through the second opening portion 126b, the first opening portion 126a, or both. [0055] Preferably, the opening means 200 includes first movement means 202 connected to gripping means 204 configured to pick up, i.e. releasably engage, said closure element 118. The first movement means 202 are configured to move between an idle position in which the gripping means 204 are spaced from said closure element 118, without engaging it (see Fig. 1 ), a first position in which the gripping means 204 are adapted to take said closure element 118 (see Fig. 2), and a second position in which said closure element 118 is moved when engaged, that is, held, by the gripping means 204 (see Fig. 3), therefore opening the vibro-feeder container 110.

[0056] In the present embodiment, the gripping means 204 include two gripping arms 206 that are movable so as to engage, i.e. to hold, the closure element 118. In particular, the gripping arms 206 are configured to move, by means of an actuating mechanism 208, between a gripping position in which they engage, preferably, the edge region of the closure element 118, and a spread-out position in which they do not engage, i.e. they free, the closure element 118.

[0057] Preferably, the first movement means 202 include respective actuation means 210, such as for example one or more actuating devices (in the drawings, they are three pneumatic systems, or alternatively they are motor-driven), that are adapted to move the gripping means 204 along and/or around respective axes of motion.

[0058] In particular, the actuation means 210 of the first movement means 202 are adapted to guide the gripping means 204 between said idle position in which the gripping means 204 are spaced from and do not engage said closure element 118 (see Fig. 1 ), said first position, in which they are adapted to take said closure element 118 (see Fig. 2), and said second position, to which said closure element 118 is moved, when engaged by the gripping means 204 (see Fig. 3), thus opening the vibro-feeder container 110.

[0059] In the present embodiment, the opening means 200 also comprise unlocking means 212 configured to cooperate with the releasable locking means 130 of the vibro-feeder container 110 to cause the movement from said locking position to said unlocking position, when the first movement means 202 are in said first position and the gripping means 204 engage the closure element 118. [0060] Preferably, the unlocking means 212 are pressure devices arranged on the gripping arms 206 in positions that operatively correspond to the pressure portions 134b of the lever elements 134 of the releasable locking means 130. Specifically, when the gripping means 204 engage the closure element 118, the unlocking means 212 are configured to apply and preferably maintain on the pressure portions 134b a pressure or force adapted to overcome the force exerted by the pressure elements 136 obtaining the release position of the releasable locking means 130.

[0061] Preferably, the opening means 200 also comprise a reading device 214, such as a code reader, a radio-frequency reader, a magnetic reader or the like, that is configured to acquire information from the identification means 146 of the vibro-feeder container 110, preferably when the latter is engaged by the gripping arms 206. In this state, advantageously, a traceability of the pharmaceutical products and their reliable processing is guaranteed through the feeding apparatus 10.

[0062] Moreover, preferably, the opening means 200 comprise one or more open/closed sensors 216, such as for example inductive sensors arranged on gripping arms 206, that are configured to monitor the position of the releasable locking means 130 and/or the degree of opening or closing of the closure element 118 of the vibro-feeder container 110. In this state, advantageously, is further guaranteed the reliability of operation of the feeding apparatus 10.

[0063] With reference to Figs. 1 to 4 and 14, the pickup section 300 is configured, preferably in the automatic mode, to receive the pharmaceutical products leaving the vibro-feeder container 110 through the opening 126, i.e. through the second opening portion 126b. In particular, in this embodiment, the pickup section 300 is configured to receive the pharmaceutical products, preferably in a singularized state, in the collecting region CR before they are collected by pickup means 400, as will be better explained later.

[0064] Preferably, the pickup section 300 comprises second movement means 302 connected to a pickup base 304 defining at least partially said collecting region CR. The pickup base 304 is configured to receive at the collecting region CR the pharmaceutical products exiting the vibro-feeder container 110 through the second opening portion 126b.

[0065] In particular, the the second movement means 302 are configured to move between a separating position in which the pickup base 304 is spaced from the bowl element 116 (see Fig. 1 ), and a collecting position in which the pickup base 304 is substantially in abutment against the bowl element 116, i.e. it engages the latter, so as to receive at the collecting region CR the pharmaceutical products leaving the vibro-feeder container 110 through the seconds opening portion 126b (see Figs. 2 and 3). Advantageously, in this state, the feeding apparatus 10 guarantees a simple and intuitive use. In fact, the vibro-feeder container 110 can be easily placed/connected by a user on the vibration unit 112 of the vibro-feeder system 100, when the pickup base 304 is in the separating position, since an appropriate maneuvering and handling space is provided. Subsequently, at the completion of the placing/connecting operation carried out by the user, the pickup base 304 can move to the collecting position to reliably process the plurality of pharmaceutical products, as will be better explained below.

[0066] Preferably, the second moving means 302 comprise respective actuation means 306, such as for example one or more actuating devices (in the drawings are shown a pneumatic system, or alternatively a motor-driven actuator) that are adapted to move the pickup base 304 along and/or around respective axes of movement.

[0067] Preferably, the pickup base 304 comprises a seat 308 defining at least partially said collecting region CR, such as for example a groove, that is appropriately shaped to receive the pharmaceutical products with a given arrangement. Specifically, the shape and/or size of the seat 308 can be widely selected in the design phase based on the shape and/or size of the pharmaceutical products. In a preferred embodiment, the seat 308 is configured to receive a single pharmaceutical product, i.e. singularized, as it comes out of the second opening portion 126b of the vibro-feeder container 110. However, this selection is not limitative and the seat 308 may provide for further configurations. For example, the seat 308 can be configured to receive more pharmaceutical products that leave the seconds opening portion 126b and that are arranged in alignment with each other.

[0068] Moreover, in the present embodiment, the pickup base 304 preferably comprises an interchangeable portion 310 that is provided with said seat 308 and that can be removably fastened to the pickup base 304. In this state, it is possible to provide a plurality of interchangeable portions 310 provided with different seats 308 having shapes and/or dimensions different from each other, so that they can be selected on the basis of the shape and/or size of different pharmaceutical products to be processed by the feeding apparatus 10. Preferably, the interchangeable portion 310 can be installed in the pickup base 304 using quick coupling means.

[0069] Moreover, the pickup section 300 of the feeding apparatus 10 preferably comprises monitoring means 312 configured to verify a given condition, preferably predetermined, for the pharmaceutical products that reach the collecting region CR. For example, the monitoring means 312, such as a meter, a sensor, a camera or the like, are configured to verify the presence of the pharmaceutical products having a given arrangement (for example singularized) and/or orientation and/or a correspondence with a preset parameter (for example shape or color within given tolerance limits), and the like.

[0070]Therefore, on the basis of the result of verification of the given condition through the monitoring means 312, the feeding apparatus 10 can appropriately adjust the activation of the pickup means 400, as will be better explained below. Advantageously, in this state, the feeding apparatus 10 guarantees a reliable processing of the pharmaceutical products through the pickup means 400, being capable of appropriately adjusting their operation.

[0071] For example, the feeding apparatus 10 activates the pickup means 400 only when the pharmaceutical products are actually present in the collecting region CR, preferably in a given arrangement. If necessary, the feeding apparatus 10 can adjust the activation of the pickup means 400 and correct its movements on the basis of the result of the verification of the given condition through the monitoring means 312. Alternatively, the feeding apparatus 10 activates the pickup means 400 so as to pick up and discard the pharmaceutical products that are not within given limits of tolerance for a preset parameter. In this state, advantageously, is further guaranteed the reliability of operation of the feeding apparatus 10.

[0072] Moreover, preferably, the pickup section 300 comprises one or more installation sensors 314 configured to identify the type of interchangeable portion 310 and/or its correct installation on the pickup base 304. In this state, the feeding apparatus 10 can verify the conformity of the characteristics of the seat 308, defining said collecting region CR, on the basis of the information on the pharmaceutical products obtained from the reading of the identification means 146 of the vibro-feeder container 110 through the reading device 214 of the opening means 200. In this state, advantageously, is further guaranteed the reliability of processing through the feeding apparatus 10.

[0073] Preferably, the pickup section 300 also comprises one or more shields 316 configured to at least partially shield the cavity 124 of the bowl element 116 from the environment external to the vibro-feeder container 110. In particular, the shields 316 are configured to shield the cavity 124 when the vibro-feeder container 110 is opened by means of the opening means 200 and the pickup base 304 is in the collecting position to receive in the collecting region CR the pharmaceutical products that exit through the second opening portion 126b. In this state, advantageously, is further prevented or reduced the probability that foreign agents enter into the cavity 124 of the bowl element 116 during processing by means of the feeding apparatus 10.

[0074]With reference to Figs. 1 to 4 and 15, the pickup means 400 are configured to, preferably in an automatic mode, collect in a releasable manner at least one pharmaceutical product from said collecting region CR. Preferably, the pickup means 400 are configured to directly pick up one pharmaceutical product at a time from said collecting region CR.

[0075] Preferably, the pickup means 400 comprise a movement assembly 402, such as for example a robotic arm assembly provided with one or more axes of rotation and/or translation activated by respective motor units (not numbered in the figures), and a pickup unit 404 removably connectable to said movement assembly 402 through a connection system 406.

[0076] In particular, the pickup unit 404 is configured to draw in a releasable manner at least one pharmaceutical product, preferably a single pharmaceutical product at a time, from said collecting region CR.

[0077] In the present embodiment, with reference to Fig. 15, the pickup unit 404 comprises a frame assembly 408 connected to the connection system 406 and supporting a suction unit 410 configured to releasably draw, by suction, at least one pharmaceutical product, preferably a single pharmaceutical product at a time, from said collecting region CR.

[0078]The suction unit 410 comprises suction means 412, such as for example a suction system connected to a suction pump adjustable by means of a vacuum switch (the figure shows only the vacuum switch), connected in a fluidic manner to a duct element 414 by means of a tube (the latter not shown in the figure). [0079]The duct element 414 comprises an end portion 416 provided with a suction inlet 418, such as a hole, open externally of the duct element 414. The suction inlet 418 is adapted to place in fluid communication the suction means 412 with the outside through said duct element 414. Moreover, the suction inlet 418 is adapted to be engaged by at least a portion of said at least one pharmaceutical product. In this state, by appropriately adjusting the suction power through the suction means 412, it is possible to hold the pharmaceutical product by creating a vacuum inside the duct element 414, which thus is adapted to suck air from the outside through the suction inlet 418. Subsequently, by suitably interrupting or reducing the suction power of the suction means 412, it is possible to release the pharmaceutical product, for example by gravity. Preferably, the shape and size of the suction inlet 418 are appropriately selected in the design phase so as to hold the pharmaceutical product on the edge defining said suction inlet 418. In other words, the shape and size of the suction inlet 418 are appropriately selected so as to prevent the entrance of the pharmaceutical product into the cavity defined inside the duct element 414.

[0080] Preferably, the duct element 414 also comprises a sleeve portion 420 that defines the suction inlet 418. The sleeve portion 420 is flexible and has preferably a bellows structure. Thus, the sleeve portion 420 guarantees an easy drawing of the pharmaceutical products since its characteristics of flexibility make it possible to adapt the shape of the suction inlet 418 on the basis of the surface and/or orientation of the pharmaceutical product that is being engaged. In this state, advantageously, the drawing up of the pharmaceutical products is reliably guaranteed.

[0081] In addition, in the present embodiment, the duct element 414 is fastened to the frame assembly 408 through damping means 422. The damping means 422 are adapted to dampen any excessive force applied by the movement assembly 402 on a pharmaceutical product through the duct element 414 of the pickup unit 404. In this state, advantageously, is further guaranteed in a reliable manner the drawing of the pharmaceutical products, this avoiding any damage to the latter.

[0082] Preferably, the damping means 422 include a plate 424 slidable on a guide 426 that is fastened to the frame assembly 408. In particular, the plate 424 is connected in turn to the frame assembly 408 through an elastic element 428, such as a compression spring. Specifically, the plate 424 is adapted to slide along the guide 426 with a travel between a stop position where it is held in abutment on a ledge element 430 and a position of maximum deformation, or compression, of the elastic element 428.

[0083] Moreover, in a most preferred embodiment, the pickup means 400 include a blow device 432 configured to induce with greater probability the disengagement of a pharmaceutical product from the pickup means 400. In particular, the blow device 432, such as a gas injection system, is configured to direct an impulse flow of gas, such as air, nitrogen or the like, toward the end portion 416 of the duct element 414 so as to induce the disengagement of a pharmaceutical product from the suction inlet 418. In this state is reduced the probability that, upon the interruption or reduction of the vacuum inside the duct element 414 to release the pharmaceutical product, the latter remains undesirably attached or restrained in the suction inlet 418.

[0084]The operation of the feeding apparatus 10, according to a preferred embodiment of the present invention, will be described later with reference to Figs. 1 to 15.

[0085] Firstly, a plurality of pharmaceutical products is inserted in a random state into the cavity 124 of the bowl element 116 of the vibro-feeder container 110. Preferably, the plurality of pharmaceutical products consists of a plurality of the same pharmaceutical product, for example pills of a given medicine. [0086]Subsequently, the opening 126 is engaged by the closure element 118, closing reversibly the cavity 124 with respect to the outside of the vibro-feeder container 110. Preferably, in this phase the releasable locking means 130 achieve the locking position in which the displacement of the closure element 118 is prevented, that is the opening of the vibro-feeder container 110 is prevented. [0087]Then, the vibro-feeder container 110 is carried and subsequently connected to the vibration unit 112 of the vibro-feeder system 100 using the releasable fastening means 114, thus forming the feeding apparatus 10. Preferably, in this phase the container sensors 150 of the vibro feeding system 100 verify the presence of the vibro-feeder container 110, or its correct installation, if necessary enabling or disabling the next phase. Moreover, preferably, the second movement means 302 are in the separating position in which the pickup base 304 is spaced from the bowl element 116 to give the user an adequate operating and movement space to enable the user to connect the vibro-feeder container 110 on the vibration unit 112.

[0088]Subsequently, the opening means 200 engage and displace at least partially the closure element 118 of the vibro-feeder container 110 to make the cavity 124 accessible from outside (and vice-versa) through at least one portion of the opening 126, for example through the second portion of the opening 126b and part of the first opening portion 126a.

[0089] In particular, the first movement means 202 move from the idle position (see Fig. 1 ) toward the first position in which the gripping means 204 are adapted to grip the closure element 118. Then, the two gripping arms 206 of the gripping means 204 engage, or grip, the closure element 118 (see Fig. 2).

[0090] Preferably, the reading device 214 of the opening means 200 acquires the information from the identification means 146 of the vibro-feeder container 110, if necessary enabling the next phase. For example, the apparatus 10 provided with memory means (not shown in the figures) in which a working program is stored, compares said information with preset data, enabling if necessary the next phase based on the results of the comparison.

[0091]Thus, the unlocking means 212 of the opening means 200 cooperate with the releasable locking means 130 of the vibro-feeder container 110 so as to induce its movement from the locking position to the release position, in which the displacement of the closure element 118 is allowed (that is, in which the opening of the vibro-feeder container 110 is allowed).

[0092] Preferably, the open/closed sensors 216 monitor the position of the locking means 130 of the closure element 118 in the vibro-feeder container 110, if necessary enabling the next phase. For example, the apparatus 10, provided with memory means (not shown in the figures) in which are stored the processing parameters, compares said sensed position (locking or release position) with preset data, enabling if necessary the next step based on the result of the comparison.

[0093]Subsequently, the first movement means 202 move from the first position to the second position, in which the closure element 118 is moved to make the cavity 124 accessible from outside through at least a portion of the opening 126, such as the second opening portion 126b and at least a part of the first opening portion 126a (see Fig. 3). In the preferred embodiment, in this phase the closure element 118 is moved to leave the latter mainly overlapping the first opening portion 126a so as to reduce the probability that foreign agents can enter into the cavity 124 of the bowl element 116.

[0094] Preferably, the open/closed sensors 216 monitor the degree of displacement of the closure element 118 of the vibro-feeder container 110, if necessary enabling the next phase. For example, the apparatus 10, provided with memory means (not shown in the figures) in which processing parameters are stored, compares said degree of opening sensed with the preset data, enabling the subsequent phase based on the result of the comparison.

[0095] Moreover, the second movement means 302 of the pickup section 300 move from the separating position (see Figs. 1 and 2) toward the collecting position in which the pickup base 304 engages the bowl element 116 so as to receive in the collecting region CR (or in the seat 308 of the interchangeable portion 310 of the pickup base 304) the pharmaceutical products leaving the vibro-feeder container 110 through the second opening portion 126b (see Fig. 3). [0096]Then, the vibration actuating system 144 of the vibration unit 112 of the vibro-feeder system 100 is actuated to generate a vibrational movement. In this state, said vibrational movement is applied, that is transmitted, by the bowl element 116 to induce a movement of the pharmaceutical products from the bottom 122 toward the collecting region CR through the path 128.

[0097] Preferably, the monitoring means 312 verify a given preset condition for the pharmaceutical products that reach the collecting region CR, if necessary enabling the subsequent phase. For example, the apparatus 10, provided with memory means (not shown in the figures) in which are stored processing parameters, verifies if there is effectively in the collecting region CR a single pharmaceutical product, enabling if necessary the subsequent step based on the result of the verification. Flowever, it is possible to provide other types of conditions that can be verified by the monitoring means 312. [0098]Subsequently, the pickup means 400 can be actuated to releasably pick up at least one pharmaceutical product, preferably a single pharmaceutical product at a time, from the collecting region CR.

[0099] In particular, the movement assembly 402 moves the pickup unit 404 so as to engage the suction inlet 418 of the duct element 414 with a pharmaceutical product. In this state, the pharmaceutical product is held by actuating the suction means 412 and properly adjusting the suction power.

[0100]Then, by further moving the movement assembly 402, the pharmaceutical product is carried toward other processes and/or equipment (not shown in the figures) and released there by interrupting or properly reducing the suction power of the suction means 412. For example, the pickup means 400 can carry the pharmaceutical product to a machine for its insertion inside a blister of a packaging support, or inside another type of packaging.

[0101] Preferably, to favor the release of the pharmaceutical product, the blow device 432 directs an impulse flow of gas substantially toward the end portion 416 of the duct element 414.

[0102] Afterward, the pickup means 400 can act repeatedly on a plurality of pharmaceutical products as they reach the collecting region CR to carry them toward other processes and/or machines (not shown in the figures), as previously mentioned.

[0103] In other embodiments, the vibration actuating system 144 of the vibration unit 112 can be temporarily stopped during the interval of time in which the monitoring means 312 verify the given condition for the pharmaceutical products that reach the collecting region CR, and/or during their collection by the pickup means 400, so as to avoid a disturbance due to vibration and to reduce the friction between the pharmaceutical products and the formation of fine powder.

[0104] When the processing of the pharmaceutical products is completed, for example when the pharmaceutical products contained in the cavity 124 of the bowl element 116 are finished, the vibro-feeder container 110 can be closed by carrying out, preferably, the following procedure.

[0105] Firstly, the moving assembly 402 of the pickup means 400 moves the pickup unit 404 so as to maintain the suction inlet 418 of the duct element 414 far from the collecting region CR.

[0106]Then, the vibration actuation system 144 of the vibration unit 112 is disabled to interrupt the vibrational movement and, consequently, the movement of any pharmaceutical products from the bottom 122 toward the collecting region CR through the path 128.

[0107]Subsequently, the movement means 302 of the drawing section 300 move from the collecting position (see Fig. 3) toward the separating position in which the pickup base 304 is spaced from the vibro-feeder container 110 (see Figs. 1 and 2).

[0108]Then, the first movement means 202 of the opening means 200 move from the second position (see Fig. 3) to the first position, in which the closure element 118 engages the opening of the bowl element 116 (see Fig. 2).

[0109]The unlocking means 212 of the opening means 200 disengage from the releasable locking means 130 of the vibro-feeder container 110 so as to induce its movement from the release position to the locking position, in which the displacement of the closure element 118 is prevented (that is, in which the opening of the vibro-feeder container 110 is prevented).

[0110]Then, the two gripping arms 206 of the gripping means 204 free the closure element 118, and the first movement means 202 of the opening means 200 move from the first position to the second idle position, in which the gripping means 204 are distant from and do not engage the closure element 118 (see Fig. 1 ).

[0111 ] In this state, it is possible to disconnect the vibro-feeder container 110 from the vibration unit 112 by operating on the releasable fastening means 114.

[0112] It is clear that it is possible to provide other embodiments without departing from the scope of the claims.

[0113] For example, in the previously described embodiment, the collecting region CR is defined by the seat 308 of the pickup base 304 of the pickup section 300, that is, the seat 308 of the interchangeable portion 310.

[0114]Flowever, it is possible to provide an embodiment in which, as shown in Fig. 16, the pickup section is not provided and the collecting region CR is defined by a portion of the path 128 of the bowl element 116 of the vibro-feeder container 110. For example, inside the cavity 124, the path 128 can be provided with an end portion defining the collecting region CR in which a stop element is provided, such as a wall projecting from the path 128, that forms at least partially a seat for collecting the pharmaceutical products using the pickup means 400.

[0115]Thus, in this case, the pickup means 400 are configured to pick up in a releasable manner at least one pharmaceutical product from a collecting region CR arranged substantially on the path 128, inside the cavity 124 of the bowl element 116 of the vibro-feeder container 110. It appears clear that, in this case, the opening means 200 are configured to engage and displace at least partially the closure element 118 so as to make said collecting region CR accessible to the pickup means 400 through at least a portion of the opening 126, for example through the first portion 126a of the opening. Furthermore, in this case, it is possible to provide that monitoring means 312 verify a given condition for the pharmaceutical products that reach said collecting region CR arranged substantially inside the cavity 124.

[0116] In a further preferred embodiment, the pickup base 304 of the pickup section 300, or its interchangeable portion 310, is provided with a projecting element configured to engage the second opening portion 126b of the bowl element 116 of the vibro-feeder container 110 when the pickup section 300 is in said collecting position. In particular, in said collecting position, said projecting element is configured to intercept the path 128 at the second opening portion 126b acting as stop element adapted to receive in abutment the pharmaceutical products that move along the path 128. In this state, said stop element forms the seat 308 defining at least partially the collecting region CR, jointly with the respective portion of the path 128, for collecting the pharmaceutical products by way of the pickup means 400.

[0117]The embodiments that envision the pickup section 300, advantageously guarantee a greater reliability in the collecting phase of the pharmaceutical products from the collecting region CR by means of the pickup means 400. In fact, in this case, the vibrational movement of the vibro-feeder system 100 is not transmitted, or is reduced, at the collecting region CR and, consequently, the collection with the pickup means 400 is more precise.

[0118] Moreover, in the preceding description the pickup section 300 comprises a seat 308 configured to receive preferably a single, i.e. singularized, pharmaceutical product. However, this construction is not limitative and the seat 308 can provide for other constructions. For example, the seat 308 can be defined by a seat or an elongate groove configured to receive pharmaceutical products arranged along a single row, when they reach the opening 126 or a portion of the same, such as for example the second opening portion 126b. In this case, the collecting region CR is defined by at least a part of said seat or groove.

[0119] Moreover, in the preceding description the pickup means 400 are configured to collect a single pharmaceutical product at a time from the collecting region CR. However, it is possible to provide an embodiment in which the pickup means 400 are configured to simultaneously collect two or more pharmaceutical products (for example two) when the collecting regions CR is adapted to collect more than one pharmaceutical product. For example, in this case the suction inlet 418 of the duct element 414 of the suction unit 410 can be configured to be engaged simultaneously by two or more pharmaceutical products (for example two) that are adjacent to each other in the collecting region CR.

[0120] Moreover, in the preceding description, the feeding apparatus 10 comprises both the pickup section 300 and the pickup means 400. However, it is possible to provide an embodiment in which the pickup means 400 are not provided and the collecting region CR is defined by a part of a pickup section that provides other kind of constructions with respect to the one previously described. For example, the pickup section can include a chute appropriately shaped to receive the pharmaceutical products in a given arrangement, for example arranged along a single row, when they leave the vibro-feeder container 110 through the opening 126 or a portion of the same, such as for example the second opening portion 126b. In this case, the collecting region CR is defined by one part of said chute, such as an end part of the same arranged below the opening 126 to receive the pharmaceutical products by gravity.

[0121] Moreover, in the preceding description the monitoring means 312 are associated to the collecting region 300. However, it is possible to provide embodiments in which the monitoring means 312 are associated to other components of the feeding apparatus 10. For example, the monitoring means 312 can be associated alternatively to the vibro-feeder system 100, to the opening means 200 or to the pickup means 400, or they can be provided as being independent from the same.

[0122] In addition, in the preceding description the unlocking means 212, the reading device 214, and the open/closed sensors 216 are associated to the opening means 200. However, it is possible to provide embodiments in which the unlocking means 212 and/or the reading device 214 and/or the open/close sensors 216 are associated to other components of the feeding apparatus 10. For example, the unlocking means 212, the reading device 214, and the open/closed sensors 216 can be associated to the vibration unit 112 of the vibro- feeder system 100, or they can be provided independent of both the latter and of the opening means 200.

[0123] Moreover, in the preceding description, the feeding apparatus 10 includes pickup means 400 provided with a suction unit 410 configured to releasably collect by suction the pharmaceutical products from the collecting region CR. However, the pickup means 400 can provide for other constructions. For example, it is possible to provide, in place of the suction unit 410, a mechanical unit comprising a gripping element configured to releasably catch the pharmaceutical products from the collecting region CR.

[0124] In addition, in the preceding description, the vibro-feeder container 110 has a bowl-like element 116 having the substantially the shape of a truncated cone. However, this selection is not limitative and the bowl element 116 can provide for other constructions. For example, the bowl element 116 can be a cylindrical hollow container in which the lateral wall substantially defines said wall 120, a base substantially defines the bottom 122, and the other base substantially defines the opening 126.

[0125] Moreover, in the preceding description, the bowl element 116 of the vibro- feeder container 110 includes the opening 126 defined by the first opening portion 126a and by the second opening portion 126b. However, this selection is not limiting and the bowl element 116 of the vibro-feeder container 110 can comprise an opening 126 defined only by one between the first opening portion 126a and the second opening portion 126b. For example, the bowl element 116 can be a cylindrical hollow container in which the opening 126 is formed only in one of its two bases, and the closure element 118 is an openable cover or door adapted to engage this opening. Alternatively, the bowl element 116 can be a cylindrical hollow container in which the opening 126 is formed only on its lateral wall, and the closure element 118 is an openable cover or door adapted to engage said opening.

[0126] From what has been described hereto, it is evident that important results have been achieved, making it possible to implement a feeding apparatus 10 configured to receive pharmaceutical products in a random state and subsequently supply them with a given arrangement, for example singularized, preventing or reducing the probability of their being contaminated and/or altered by foreign agents.

[0127] Moreover, the feeding apparatus 10 reliably guarantees the provision of pharmaceutical products according to a given arrangement. In fact, the path 128 and the collecting region CR, i.e. the seat 308, can be appropriately shaped on the basis of the arrangement of the pharmaceutical products aimed at.

[0128] In addition, the feeding apparatus 10 guarantees reliable processing of a plurality of pharmaceutical products received in a random state. In particular, the vibro-feeder container 110 and it elements, such as for example the bowl element 116 and the path 128, can be appropriately shaped to allow a reliable processing of a plurality of pharmaceutical products received in a random state.

[0129] Moreover, the feeding apparatus 10 prevents or reduces any contamination and/or alteration of the pharmaceutical products. In fact, the use of an openable vibro-feeder container 110 prevents or reduces a contamination and/or alteration of the pharmaceutical products both during their processing by means of the feeding apparatus 10, and in the steps that precede said processing, for example during preceding steps of storage or transportation.

[0130] In particular, the releasable locking means 130 of the vibro-feeder container 110 further guarantee in a reliable manner a closure, i.e. a protection, of the cavity 124 containing the pharmaceutical products during the steps that precede processing by means of the feeding apparatus 10.

[0131] Moreover, advantageously, the vibro-feeder container 110 can be reused a number of times, filling it with a plurality of pharmaceutical products that are each time of different type, after prior cleaning and/or decontamination procedure between one filling and the next to avoid contaminations and/or alterations.

[0132] In addition, the use of opening means 200 of the feeding apparatus 10 reduces the number of steps that call for a handling by a user and, consequently, prevents or reduces a contamination and/or alteration of the pharmaceutical product. In particular, the unlocking means 212 of the opening means 200 allow the opening of the vibro-feeder container 110 when it is associated to the feeding apparatus 10. Preferably, the vibro-feeder container 110 provides for releasable locking means 130 configured so as not to be manually accessible to a user or in any case to make it improbable to have an accidentally opening of the vibro- feeder container 110.

[0133] Moreover, the vibro-feeder container 110 is configured to operate in association with said feeding apparatus 10 to prevent or reduce a contamination and/or alteration of the pharmaceutical products and, at the same time, allow a reliable processing of the plurality of pharmaceutical products.

[0134] In particular, the vibro-feeder container 110 can be appropriately designed on the basis, for example, of the characteristics of shape and dimensions of the pharmaceutical products and, at the same time, protects the latter in the steps that precede the processing itself, for example during previous steps of storage or transportation.

[0135] Moreover, the vibro-feeder container 110 and the feeding apparatus 10 provide for a simple and intuitive use on the part of a user, thus avoiding accidental errors.

[0136] Moreover, the feeding apparatus 10 and the vibro-feeder container 110 provide for constructions that are simple to achieve and widely adaptable on the basis of specific design requirements.

[0137] In particular, the feeding apparatus 10 and the vibro-feeder container 110 are suitable for handling or processing systems configured to achieve a singularization of the pharmaceutical products.

[0138] Naturally, the materials and equipment used to achieve the present invention, as well as the shape and dimensions of the individual components, can be the most suitable for the specific requirements.