FIBER ARRAY FOR OPTICAL IMAGING AND THERAPEUTICS

WIPO Patent Application WO/2010/099548

A3

The present invention relates to the field of optical imaging and therapeutics. More particularly, embodiments of the present invention provide minimally-invasive Fiberoptic Microneedle Devices (FMDs) for light-based therapeutics, which physically penetrate tissue and deliver light directly into the target area below the skin surface (FIG. 1). A preferred embodiment of the invention is a fiberoptic microneedle device comprising: (a) one or more silica-based needles capable of guiding light and comprising a length of about 0.5-6 mm, a base having an outer diameter in the range of about 100-150 micron, and a tip having an outer diameter in the range of about 5-20 micron; (b) a support member to which the needles are secured; (c) a ferrule comprising one or more holes for each of the needles, wherein the ferrule is operably configured to provide mechanical support to each needle at all or some portion of the length of the needle. Embodiments of the invention enable depth-selective and deep photothermal therapeutics and can be adapted for use with any laser-based treatment or diagnostic in which light is used to detect or treat targets under or on the skin surface.

RYLANDER CHRISTOPHER (US)
CAMPBELL THOMAS A (US)
WANG GE (US)
XU YONG (CN)
KOSOGLU MEHMET ALPASLAN (TR)

PCT/US2010/025809

January 13, 2011

March 01, 2010

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VIRGINIA TECH INTELL PROP (US)
RYLANDER CHRISTOPHER (US)
CAMPBELL THOMAS A (US)
WANG GE (US)
XU YONG (CN)
KOSOGLU MEHMET ALPASLAN (TR)

A61N5/06; A61N5/067; G02B6/04; G02B6/06

US20050137531A1	2005-06-23
US20030095582A1	2003-05-22
US20070129713A1	2007-06-07
US20080140023A1	2008-06-12
US20080269735A1	2008-10-30

MAYBERRY, Michele, L. (PO Box 10944Blacksburg, VA, US)

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