Title:
FIBRIN SEALANTS PROVIDING LESS INFLAMMATORY RESPONSE AND METHODS USING SAME
Document Type and Number:
WIPO Patent Application WO2000072856
Kind Code:
A9
Abstract:
In accordance with the present invention novel fibrin sealants which provoke less of any inflammatory response than prior art sealants, and methods of using such sealants, are disclosed. It has now been found that fibrin sealants can be prepared in a number of ways to selectively include or exclude components which are presently understood to upregulate or downregulate the body's natural inflammatory response. The novel sealants of this invention are useful in any instance where fibrin sealants have known utility. Nonlimiting examples include use in hemostasis, sealing of fluid or air leaks, delivery of cells, tissue repair and wound healing, drug delivery and particularly useful in the prevention of post surgical adhesion formation.
Inventors:
FAIRBROTHER JOHN E
SCOTT NIGEL
WALKER MICHAEL
SCOTT NIGEL
WALKER MICHAEL
Application Number:
PCT/US2000/015139
Publication Date:
April 18, 2002
Filing Date:
June 01, 2000
Export Citation:
Assignee:
BRISTOL MYERS SQUIBB CO (US)
International Classes:
A61L24/00; A61K38/36; A61L24/10; A61L31/04; A61P43/00; (IPC1-7): A61K35/14; A61K31/34; A61K38/00; A61K38/46; A01N37/12; A01N37/44; A01N43/08; C08G63/48; C08G63/91
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