Title:
FLUORESCENT MOLECULE
Document Type and Number:
WIPO Patent Application WO/2008/075718
Kind Code:
A1
Abstract:
A fluorescent compound of the fluorescence on-off type for gene analysis. It has high stability and high sensitivity and amplifies a trace genetic signal to an observable level. The compound is represented by the following formula (1) or (2). (In the formulae, R1 represents C1-6 alkyl, amino, optionally protected or substituted amide, halogeno, or hydrogen; R2's each independently represents C1-6 alkyl, halogeno, or hydrogen; and R3 represents C1-6 alkyl, aryl, or hydrogen and R4 represents an oxygen-containing group or hydrogen, provided that R3 and R4 may be bonded to each other to form a ring.)
Inventors:
ABE HIROSHI (JP)
ITO YOSHIHIRO (JP)
WANG JIN (JP)
FURUKAWA KAZUHIRO (JP)
ITO YOSHIHIRO (JP)
WANG JIN (JP)
FURUKAWA KAZUHIRO (JP)
Application Number:
PCT/JP2007/074424
Publication Date:
June 26, 2008
Filing Date:
December 19, 2007
Export Citation:
Assignee:
RIKEN (JP)
ABE HIROSHI (JP)
ITO YOSHIHIRO (JP)
WANG JIN (JP)
FURUKAWA KAZUHIRO (JP)
ABE HIROSHI (JP)
ITO YOSHIHIRO (JP)
WANG JIN (JP)
FURUKAWA KAZUHIRO (JP)
International Classes:
C07D493/10; C09B11/28; C12Q1/04; C12Q1/68; G01N33/50; G01N33/536
Domestic Patent References:
| WO2000003033A1 | 2000-01-20 |
Foreign References:
| JP2004532805A | 2004-10-28 | |||
| JP2005047898A | 2005-02-24 | |||
| JP2002034595A | 2002-02-05 |
Other References:
NOVIKOVA E.A. ET AL.: "Synthesis and structure of some azidofluoran derivatives", RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, vol. 34, no. 12, 1998, pages 1762 - 1767, XP008110139
AMANN ET AL., J. BACTERIOL., vol. 172, 1990, pages 762 - 770
AMANN ET AL., J. BACTERIOL., vol. 172, 1990, pages 762 - 770
Attorney, Agent or Firm:
SIKs & Co. (Kyobashi-Nisshoku Bldg.8-7, Kyobashi 1-chom, Chuo-ku Tokyo 31, JP)
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